COURSE SYLLABUS

TERATOLOGY

1	Course Title:	TERATOLOGY
2	Course Code:	THE5017
3	Type of Course:	Optional
4	Level of Course:	Second Cycle
5	Year of Study:	1
6	Semester:	1
7	ECTS Credits Allocated:	2
8	Theoretical (hour/week):	1
9	Practice (hour/week) :	0
10	Laboratory (hour/week) :	0
11	Prerequisites:	None
12	Recommended optional programme components:	None
13	Language:	Turkish
14	Mode of Delivery:	Face to face
15	Course Coordinator:	Prof. Dr. ZEHRA MİNBAY
16	Course Lecturers:	Prof. Dr. Zehra MİNBAY Doç. Dr. Berrin AVCI
17	Contactinformation of the Course Coordinator:	zminbay@uludag.edu.tr (224) 295 40 64 Bursa Uludağ Üniversitesi Tıp Fakültesi Histoloji ve Embriyoloji AD 16059 Nilüfer Bursa
18	Website:
19	Objective of the Course:	Teach the causes of human developmental disorder, ensure that anomalies caused by environmental and genetic factors are known and teach what can be done to prevent congenital malformations or what should not be done.
20	Contribution of the Course to Professional Development	This course is important in terms of gaining basic knowledge within the scope of in master degree education.

Learning Outcomes:

1	Explains the principles of teratology and the importance of developmental timing of exposure to teratogens;
2	Learn the genetic and environmental factors that cause congenital malformations;
3	Categorize teratogens and know their teratogenic effects;
4	Explain the concepts of aneuploidy, triploidy, and tetraploidy and the roles of mutant genes in causing birth defects;
5	Explain the difference between a malformation and a deformation;
6	Understand the importance of maternal health and its effects on offspring and learn the exposures to be avoided during and prior to pregnancy;

22	Course Content:

Week	Theoretical	Practical
1	The meaning of teratology, the principles of teratology and critical periods of human development
2	Birth defect prevalence, classification and causes of birth defects
3	Birth defects caused by genetic factors 1
4	Birth defects caused by genetic factors 2
5	Drugs as teratogens 1 - Mechanisms of teratogenic effects of drugs
6	Drugs as teratogens 2 - Teratogenic drugs
7	Drugs as teratogens 3 - Teratogenic drugs
8	Drugs as teratogens 4 – Specification of drug teratogenicity
9	Infectious agents as teratogens
10	Environmental chemicals, radiation, and ultrasonic waves as teratogens
11	Maternal factors and mechanical factors as teratogens 1
12	Maternal factors and mechanical factors as teratogens 2 and male-mediated teratogenesis
13	Birth defects caused by multifactorial inheritance
14	Prenatal diagnosis

23	Textbooks, References and/or Other Materials:	1. Sadler T.W. Langman’s Medical Embryology. 13th edition, China: Wolters Kluwer Health; 2015. 2. Carlson BM. Human Embryology and Developmental Biology. 5th edition. Saunders; 2014. 3. Moore Keith L., Persaud TVN, Torchia MG. The Developing Human. 10th Edition, Philadelphia: Elsevier; 2016. 4. Schoenwolf GC, Bleyl SB, Brauer PR, Francis-West PH. Larsen’s Human Embryology. 5th Ed. Philadelphia: Churchill Livingstone;2015. 5. Pandya PP, Oepkes D, Sebire NJ, Wapner RJ. Fetal Medicine_ Basic Science and Clinical Practice. 2rd edition. China: Elsevier; 2020. 6. Gupta RC. Reproductive and Developmental Toxicology. London: Academic Press; 2011. 7. Hood, RD. Developmental and Reproductive Toxicology - A Practical Approach. 3rd edition. London: Informa Healthcare; 2012.
24	Assesment

TERM LEARNING ACTIVITIES	NUMBER	PERCENT
Midterm Exam	0	0
Quiz	0	0
Homeworks, Performances	0	0
Final Exam	1	100
Total	1	100
Contribution of Term (Year) Learning Activities to Success Grade		0
Contribution of Final Exam to Success Grade		100
Total		100
Measurement and Evaluation Techniques Used in the Course	Measurement and evaluation are performed according to the Rules & Regulations of Bursa Uludağ University on Undergraduate Education.
Information

ECTS / WORK LOAD TABLE

CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS

LO: Learning Objectives

PQ: Program Qualifications

Contribution Level:

1 Very Low

2 Low

3 Medium

4 High

5 Very High