1	Course Title:	PROTEIN AND ENZYME BIOCHEMISTRY
2	Course Code:	MBG5415
3	Type of Course:	Optional
4	Level of Course:	Second Cycle
5	Year of Study:	1
6	Semester:	1
7	ECTS Credits Allocated:	6
8	Theoretical (hour/week):	3
9	Practice (hour/week) :	0
10	Laboratory (hour/week) :	0
11	Prerequisites:	None
12	Recommended optional programme components:	None
13	Language:	Turkish
14	Mode of Delivery:	Face to face
15	Course Coordinator:	Prof. Dr. SEZAİ TÜRKEL
16	Course Lecturers:	Yok
17	Contactinformation of the Course Coordinator:	Prof.Dr. Sezai Türkel sturkel@uludag.edu.tr
18	Website:
19	Objective of the Course:	To teach structure and functions of amino acids and proteins, to teach biochemical principles of enzyme reactions and control mechanisms, to teach industrial applications of enzymes
20	Contribution of the Course to Professional Development

21

Learning Outcomes:

1 Knows structure and functions of amino acids and proteins; 2 Knows protein isolation and analysis methods; 3 Knows biological functions of amino acids and proteins; 4 Knows control mechanisms of enzyme reactions; 5 Knows enzyme kinetics; 6 Knows industrial applications of enzymes;

22	Course Content:

Week	Theoretical	Practical
1	Introduction, chemical features of amino acids and proteins
2	Classifications and biochemical features of amino acids, acid-base chemistry and titration of amino acids
3	Modifications of proteins and amino acids, amino acid derivatives and biological significance
4	Protein structures, protein folding, peptide sequencing
5	Peptide synthesis by chemical methods, non-ribosomal protein synthesis
6	Half-lives of proteins, N-end rule, proteases and ubiquitin proteosome system
7	Enzyme classifications, general features of enzymes
8	Principles of enzyme kinetics, enzymatic catalyse
9	Single and multi-substrate enzymes, allosteric enzymes and reaction mechanisms
10	Control mechanisms of enzymatic reactions, enzyme inhibition
11	Structure and functions of co-enzymes and co-factors in enzyme reactions
12	Multi-layered regulation of biochemical pathways such as glycolytic pathways
13	Production and purification of enzymes
14	Industrial applications of enzymes, enzyme immobilization

23	Textbooks, References and/or Other Materials:	1- Lehninger, Biyokimyanın ilkeleri Beşinci baskıdan çeviri Palme yayıncılık, 2013. 2- Biochemistry, Geoffry L. Zubay. 4. Ed., McGrawHill, 1998. 3- Prof.Dr. Sezai Türkel, lecture notes
24	Assesment

TERM LEARNING ACTIVITIES	NUMBER	PERCENT
Midterm Exam	1	20
Quiz	0	0
Homeworks, Performances	1	20
Final Exam	1	60
Total	3	100
Contribution of Term (Year) Learning Activities to Success Grade		40
Contribution of Final Exam to Success Grade		60
Total		100
Measurement and Evaluation Techniques Used in the Course
Information

25

ECTS / WORK LOAD TABLE

Activites	NUMBER	TIME [Hour]	Total WorkLoad [Hour]
Theoretical	14	3	42
Practicals/Labs	0	0	0
Self Study and Preparation	14	4	56
Homeworks, Performances	1	17	17
Projects	0	0	0
Field Studies	0	0	0
Midtermexams	1	30	30
Others	0	0	0
Final Exams	1	35	35
Total WorkLoad			180
Total workload/ 30 hr			6
ECTS Credit of the Course			6

26	CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
PQ1 PQ2 PQ3 PQ4 PQ5 PQ6 PQ7 PQ8 PQ9 PQ10 LO1 1 4 2 4 2 1 4 4 4 4 LO2 2 1 4 4 2 2 4 4 4 4 LO3 4 3 5 4 5 5 4 3 3 3 LO4 4 4 3 5 4 1 4 3 3 3 LO5 2 1 3 5 3 2 3 3 4 4 LO6 4 5 5 4 5 5 4 4 3 5

LO: Learning Objectives

PQ: Program Qualifications

Contribution Level:

1 Very Low

2 Low

3 Medium

4 High

5 Very High