COURSE SYLLABUS

CLINICAL LABORATORY DIAGNOSIS I

1	Course Title:	CLINICAL LABORATORY DIAGNOSIS I
2	Course Code:	VET5125
3	Type of Course:	Optional
4	Level of Course:	First Cycle
5	Year of Study:	5
6	Semester:	9
7	ECTS Credits Allocated:	2
8	Theoretical (hour/week):	1
9	Practice (hour/week) :	2
10	Laboratory (hour/week) :	0
11	Prerequisites:	None
12	Recommended optional programme components:	None
13	Language:	Turkish
14	Mode of Delivery:	Face to face
15	Course Coordinator:	Prof. Dr. NAZMIYE GÜNEŞ
16	Course Lecturers:	Prof. Dr. Ayşin ŞEN Doç.Dr.Özgür ÖZYİĞİT Doç.Dr. Murat YALÇIN Prof.Dr. Bayram ŞENLİK Prof.Dr. Ü. POLAT
17	Contactinformation of the Course Coordinator:	ngunes@uludag.edu.tr 0 224 2941182 U.Ü.Veteriner Fakültesi Biyokimya ABD
18	Website:
19	Objective of the Course:	Being able to determine and interpret biochemical parameters that aid in clinical diagnosis in farm animal medicine, and interpretation and application of physiological, pathological and microbiological methods that aid in clinical diagnosis.
20	Contribution of the Course to Professional Development

Learning Outcomes:

1	Being able to select and apply biochemical parameters that aid in clinical diagnosis in diseases resulting from pathological and metabolic disorders.;
2	Being able to interpret results of biochemical values. ;
3	Being able to explain mechanisms of diseases frequently observed in farm animals.;
4	Being able to comprehend the choosing of clinical material, preserving, and obtaining biopsies in diagnosis of farm animal diseases. ;
5	Being able to utilize diagnostic methods in immune disorders and parasitic infestations frequently observed in farm animals;
6	Being able to integrate all diagnostic knowledge acquired about farm animal diseases and use in diagnosis of diseases;
7	Being able to communicate with workers and animal owners for applications regarding material and analysis .;
8	Being able to disseminate knowledge gained about clinical biochemical methods in diagnosis of farm animal diseases verbally and in writing.;

22	Course Content:

Week	Theoretical	Practical
1	Coagulation and diagnosis of clotting disorders	Determination of the clotting time with Lee-White method; Prothrombin time (PT)-Quicks one -stage method
2	Determination of protozoa and bacteria counts in rumen content, special tests related to rumen content	Determination of protozoa and bacteria counts in rumen content
3	Clinical enzymology and interpretation	Measurement of serum AST and ALT
4	Laboratory tests of liver diseases: albumin, globulin, ammonia and urea nitrogen, starvation blood ammonia tolerance test, hypo- and hyperproteinemia, diagnostic approach to hyperglobulinemia	Analysis of serum total protein and gluteraldehyde test
5	Tests of hepatic metabolism: bilirubin metabolism and icterus, diagnostic approach to urine bilirubin, urobilinogen and high serum bile acids	Ehrlich’s benzaldehyde test, determination of urobilinogen and bile acids in urine, the determination of bilirubin by using Fauchet’s test, the use of urine strips
6	Glomerular function tests: interpretation of azotemia, creatinine clearance, tubular function tests, other serum biochemical findings in renal diseases	The microscopic examination of urine sediment, interpretation of crystals found in acid and alkaline urine
7	Plasma calcium fractions, hypo- and hypercalcemia, interpretation of hypo and hyperphosphatemia	Analysis of calcium and inorganic phosphor in serum
8	Evaluation of changes at electrolytes such as sodium, potassium, chloride and magnesium	The measurement of urine chloride
9	Examination of cerebrospinal fluid and interpretation of test results	A case oriented discussion
10	Immunologic mechanisms in immune-mediated diseases, immunologic mechanisms of bovine IgE and immune complex mediated diseases	Examination of lavage samples prepared from lung materials obtained from slaughterhouses and routine necropsies
11	Cytological examination and evaluation of the tracheobronchial aspirate and bronchoalveolar lavage	Erythrocyte aglutination tests, anti-erythrocyte antibody tests, anti-nuclear antibody tests, anti- thrombocyte antibody tests, rheumatoid factor test
12	Sampling and evaluation of nasal secretions, mouth lesions, mammary gland material, rectal and vaginal excretions, transudates and exudates	Examination of materials brought to clinics, obtained from Faculty Research Farm, routine Necropsies
13	Examination and evaluation of lymphatic aspirates	Examination of lymph node samples obtained from biopsy and slaughterhouse materials
14	Laboratory diagnostic techniques and interpretation of the results in parasitic diseases	Quantitative examination techniques and their roles in parasitology

23	Textbooks, References and/or Other Materials:	Tietz Textbook of Clinical Chemistry, 3rd Ed., Burtis, C.A., Ashwood, E.R.: Saunders, Philadelphia, 1999 Klinik Laboratuvar Tanı, Turgut K. II. Baskı, İstanbul, 2002 Tıbbi Fizyoloji, Guyton, A.C., Hall J.E., Nobel Yayınevi, İstanbul, 2000 Immunology and Immunupathology of Domestic Animals, Gershwin LJ, Krakowka S, Olsen RG, Mosby, 1995 Manuel and Atlas of Fine Needle Aspiration Cytology, Orell S.R., Sterrett G.F., Walters M.N-I., Whitaker D.,Sec. Ed., Hong Kong, 1994 Veterinarmedizinische Parasitology: Schneider T. Parey Verlag, 2006.
24	Assesment

TERM LEARNING ACTIVITIES	NUMBER	PERCENT
Midterm Exam	1	40
Quiz	1	10
Homeworks, Performances	0	0
Final Exam	1	50
Total	3	100
Contribution of Term (Year) Learning Activities to Success Grade		50
Contribution of Final Exam to Success Grade		50
Total		100
Measurement and Evaluation Techniques Used in the Course
Information

ECTS / WORK LOAD TABLE

Activites	NUMBER	TIME [Hour]	Total WorkLoad [Hour]
Theoretical	14	1	14
Practicals/Labs	14	2	28
Self Study and Preparation	4	1	4
Homeworks, Performances	0	0	0
Projects	0	0	0
Field Studies	0	0	0
Midtermexams	1	3	3
Others	1	3	3
Final Exams	1	8	8
Total WorkLoad			60
Total workload/ 30 hr			2
ECTS Credit of the Course			2

CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS

	PQ1	PQ2	PQ3	PQ4	PQ9	PQ10
LO1	4	0	3	0	0	0
LO2	0	0	4	4	0	0
LO3	4	0	0	0	0	0
LO4	0	0	3	3	0	0
LO5	0	0	3	3	0	0
LO6	5	0	0	0	0	0
LO7	0	4	0	0	3	0
LO8	0	0	0	0	0	4

LO: Learning Objectives

PQ: Program Qualifications

Contribution Level:

1 Very Low

2 Low

3 Medium

4 High

5 Very High