ANTIMICROBIAL EFFECTS AND MECHANISMS OF RESISTANCE
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Course Title:
ANTIMICROBIAL EFFECTS AND MECHANISMS OF RESISTANCE
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Course Code:
TMK6009
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Type of Course:
Optional
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Level of Course:
Third Cycle
5
Year of Study:
1
6
Semester:
1
7
ECTS Credits Allocated:
5
8
Theoretical (hour/week):
2
9
Practice (hour/week) :
0
10
Laboratory (hour/week) :
0
11
Prerequisites:
Optional
12
Recommended optional programme components:
None
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Language:
Turkish
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Mode of Delivery:
Face to face
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Course Coordinator:
Prof. Dr. EMİN HALİS AKALIN
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Course Lecturers:
Prof Dr Halis Akalın Prof Dr Sibel Gürün Prof Dr Cüneyt Özakın Doç Dr Melda Sınırtaş
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Contactinformation of the Course Coordinator:
halis@uludag.edu.tr 0224 295 0315 Uludağ Üniversitesi Tıp Fakültesi Enfeksiyon Hastalıkları Anabilim Dalı 16059 Görükle Bursa
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Website:
http:/www.uludag.edu.tr
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Objective of the Course:
Be able to classify the antibiotics and synthetic antimicrobial agents, to comprehend the mechanisms of action of antimicrobials and bacterial resistance mechanisms developed against them
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Contribution of the Course to Professional Development
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Learning Outcomes:
1
To classify the antimicrobials and to learn the historical development of antibacterial treatment;
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To learn the antibacterials and mechanisms of effect;
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To learn the concepts of MIC, MBC, bacteriostatic and bactericidal effects ;
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To learn the pharmacokinetic and pharmacodynamic of antibacterials;
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To learn and comment the in vitro susceptibility tests;
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To learn and comment the in vitro synergy tests;
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To understand the public health problems due to antibacterial resistance;
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Course Content:
Week
Theoretical
Practical
1
Antimicrobials: Overview
2
Antibacterials and mechanisms of effect
3
Beta-lactams
4
Macrolides
5
Aminoglycosides
6
Quinolones
7
Glycopeptides
8
Tetracyclines and others
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Development of resistance to antibacterials and resistance mechanisms
10
In vitro antibacterial susceptibility tests
11
In vitro antibacterial synergy tests
12
Pharmacokinetic and pharmacodynamic of antibacterials
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From laboratory to clinic. Work with together
14
Stewardship of antibacterial usage
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Textbooks, References and/or Other Materials:
Murray PR, Rosenthal KS, Pfaller MA. Medical Microbiology. 6th ed. Philladelphia:Mosby 2010 Mandell GL, Bennett JE, Dolin R. Principle and Practice of Infectious Diseases. 7th ed. Churchill-Livingstone-Elsevier 2010.
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Assesment
TERM LEARNING ACTIVITIES
NUMBER
PERCENT
Midterm Exam
1
40
Quiz
0
0
Homeworks, Performances
0
0
Final Exam
1
60
Total
2
100
Contribution of Term (Year) Learning Activities to Success Grade
40
Contribution of Final Exam to Success Grade
60
Total
100
Measurement and Evaluation Techniques Used in the Course
Information
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ECTS / WORK LOAD TABLE
Activites
NUMBER
TIME [Hour]
Total WorkLoad [Hour]
Theoretical
14
2
28
Practicals/Labs
0
0
0
Self Study and Preparation
12
8,5
102
Homeworks, Performances
0
0
0
Projects
0
0
0
Field Studies
0
0
0
Midtermexams
1
10
10
Others
0
0
0
Final Exams
1
10
10
Total WorkLoad
150
Total workload/ 30 hr
5
ECTS Credit of the Course
5
26
CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
