1	Course Title:	APOPTOSIS AND MOLECULAR APPLICATIONS
2	Course Code:	MBG4120
3	Type of Course:	Optional
4	Level of Course:	First Cycle
5	Year of Study:	4
6	Semester:	8
7	ECTS Credits Allocated:	6
8	Theoretical (hour/week):	3
9	Practice (hour/week) :	0
10	Laboratory (hour/week) :	0
11	Prerequisites:
12	Recommended optional programme components:	None
13	Language:	Turkish
14	Mode of Delivery:	Face to face
15	Course Coordinator:	Doç. Dr. BURCU ERBAYKENT
16	Course Lecturers:
17	Contactinformation of the Course Coordinator:	Dr. Ögr. Üyesi Burcu ERBAYKENT TEPEDELEN e-posta: berbaykent@uludag.edu.tr 0 224 29 42847 Fen-Edebiyat Fakültesi, Moleküler Biyoloji ve Genetik Bölümü, Görükle Kampüsü, 16059 Bursa
18	Website:
19	Objective of the Course:	In this course, the definition of apoptosis, types of cell death, activation and regulation of apoptosis, apoptosis-related diseases and treatments, and methods used in determining apoptosis are planned to explain.
20	Contribution of the Course to Professional Development	It contributes to postgraduate education in research laboratories working on this subject.

21

Learning Outcomes:

1 Defining cell death types ; 2 Knowing the definition and role of caspases ; 3 Describe the induction mechanisms of apoptosis ; 4 To know extrinsic and intrinsic pathways ; 5 Describe the role of Bcl proteins ; 6 Describe the role of extracellular survival factors in apoptosis ; 7 To know the relationship between apoptosis and diseases ; 8 Learning the methods used to determine apoptosis;

22	Course Content:

Week	Theoretical	Practical
1	Apoptosis: Overview
2	Different forms of cell death
3	Role of caspases in apoptosis
4	Caspase activation pathways: Extrinsic pathway
5	Caspase activation pathways: Intrinsic pathway
6	Apoptosis regulation: Bcl proteins
7	Apoptosis regulation: Extracellular survival factors
8	Inhibitors of apoptosis
9	Autophagy
10	Apoptosis in disease and treatment
11	Methods used in the determination of apoptosis: Morphological imaging methods
12	Methods used in the determination of apoptosis: Histochemical methods
13	Methods used in the determination of apoptosis: Biochemical methods
14	Methods used in the determination of apoptosis: Immunological methods

23	Textbooks, References and/or Other Materials:	1. When Cells Die II: A Comprehensive Evaluation of Apoptosis and Programmed Cell Death; Editors: Richard A. Lockshin, Zahra Zakeri 2. Apoptosis and Cancer: Methods and Protocols, 2nd edition; Editors: Gil Mor, Ayesha B. Alvero 3. Apoptosis, Methods and Protocols Second Edition; Editors: Peter Erhardt, Ambrus Toth
24	Assesment

TERM LEARNING ACTIVITIES	NUMBER	PERCENT
Midterm Exam	1	40
Quiz	0	0
Homeworks, Performances	0	0
Final Exam	1	60
Total	2	100
Contribution of Term (Year) Learning Activities to Success Grade		40
Contribution of Final Exam to Success Grade		60
Total		100
Measurement and Evaluation Techniques Used in the Course	Written examination
Information	The system of relative evaluation is applied.

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ECTS / WORK LOAD TABLE

Activites	NUMBER	TIME [Hour]	Total WorkLoad [Hour]
Theoretical	14	3	42
Practicals/Labs	0	0	0
Self Study and Preparation	14	4	56
Homeworks, Performances	0	0	0
Projects	0	0	0
Field Studies	0	0	0
Midtermexams	1	30	30
Others	0	0	0
Final Exams	1	52	52
Total WorkLoad			180
Total workload/ 30 hr			6
ECTS Credit of the Course			6

26	CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
PQ1 PQ2 PQ3 PQ4 PQ5 PQ6 PQ7 PQ8 PQ9 PQ10 LO1 5 0 5 2 5 0 0 3 3 3 LO2 5 0 5 2 5 0 0 3 3 3 LO3 5 0 5 2 5 0 0 3 3 3 LO4 5 0 5 2 5 0 0 3 3 3 LO5 5 0 5 2 5 0 0 3 3 3 LO6 5 0 5 2 5 0 0 3 3 3 LO7 5 0 5 2 5 0 0 3 3 3 LO8 5 0 5 2 5 0 0 3 3 3

LO: Learning Objectives

PQ: Program Qualifications

Contribution Level:

1 Very Low

2 Low

3 Medium

4 High

5 Very High