COURSE SYLLABUS

POPULATION GENETICS

1	Course Title:	POPULATION GENETICS
2	Course Code:	VET2517
3	Type of Course:	Optional
4	Level of Course:	First Cycle
5	Year of Study:	2
6	Semester:	3
7	ECTS Credits Allocated:	3
8	Theoretical (hour/week):	2
9	Practice (hour/week) :	0
10	Laboratory (hour/week) :	0
11	Prerequisites:	None
12	Recommended optional programme components:	None
13	Language:	Turkish
14	Mode of Delivery:	Face to face
15	Course Coordinator:	Doç. Dr. SENA ARDIÇLI
16	Course Lecturers:	Yok
17	Contactinformation of the Course Coordinator:	Doç. Dr. Sena Ardıçlı Mail:sardicli@uludag.edu.tr Tel: 0 224 294 1307 Adres: Bursa Uludağ Üniversitesi / Zootekni ve Hayvan Besleme Bölümü / Genetik Anabilim Dalı, Görükle Kampüsü Nilüfer/BURSA
18	Website:
19	Objective of the Course:	To ensure that students of Faculty of Veterinary Medicine have knowledge about the functioning of basic molecular genetic dynamics at the level of populations and the sources of variation formed by different mechanisms. In addition, it is aimed to describe the evaluation of the economically important quantitative characters on a herd basis, eradication of hereditary diseases by using current genetic methods, and the genetic basis of genomic selection.
20	Contribution of the Course to Professional Development	To enable students of the Faculty of Veterinary Medicine to learn basic population genetics and to interpret genetic dynamics at the population level.

Learning Outcomes:

1	Gains knowledge of population, gene pool, genome, genetic variation, genotype-phenotype association;
2	Gains knowledge of natural selection, speciation mechanisms, formation and selection of subspecies, genetic drift, bottle neck effect.;
3	Gains knowledge of mutation, polymorphism, Hardy-Weinberg principles, balanced populations, reasons for deviation from Hardy-Weinberg equilibrium, continuous and discontinuous variation ;
4	Can calculate and interpret genotypic and allelic frequencies, basic population genetics parameters.;
5	Have knowledge about the evaluation of genetic variation sources on the basis of populations or herd and the potential of using these variation in selection, current genetic techniques in animal breeding and genomic selection.;
6	Can comment on different inheritance patterns and their effects at the population level.;
7	Gains knowledge of molecular evolution and phylogenetics.;
8	Be able to review and evaluate literature and presentations critically;
9	Obtain an accurate and relevant history of the individual animal or animal group, and its/their environment ;

22	Course Content:

Week	Theoretical	Practical
1	Introduction to basic concepts in population genetics and introduction to the course
2	Genetic structure of populations and gene pools
3	Multiple alleles and polymorphism, calculation of allelic frequencies, allele frequencies in mutation-selection balance
4	Hardy-Weinberg principles
5	Selection in natural populations, molecular genetic basis of natural selection
6	Mendelian genetics, selection and mutation dynamics in populations
7	Mutation, migration, genetic drift, bottle neck effect
8	Polygenic inheritance and continuous variation
9	Homozygosity and heterozygosity, heterosis, evaluation of inbreeding levels, calculation and interpretation of population genetics indexes
10	Forces changing gene frequencies, genetic systems, integration and seperation of gene pools
11	Mathematical evaluation of genetic changes in populations, statistical interpretation of genotype-phenotype relationships and association analysis
12	Speciation mechanisms
13	Molecular evolution mechanisms and their genotypic effects on populations
14	Molecular phylogenetics

23	Textbooks, References and/or Other Materials:	1. Klug W.S., Cummings M.R., Concepts of Genetics, Palme Publishing, Ankara, 2017. 2. Anthony J.F. Griffiths , Susan R. Wessler, Sean B. Carroll , John Doebley. Introduction to Genetic Analysis, 10th Edition, Palme Publishing, Ankara, 2015 (ISBN: 9786053552857). 3. Brown T.A. Genoms 3, (3rd Edition), Nobel Publishing, Ankara, 2015. 4. Falconer,D.S. & Mackay T., Introduction to Quantitative Genetics, Longman Scientific & Technical, 1996. 5. Freeman S., Herron J.C. Evolutinary analysis, 2nd Edition, Palme publishing, Ankara, 2001. 6. Spiess E.B. Genes in Populations, 2nd Edition, A Wiley-interscience publication, John Wiley & Sons, Inc, Canada, 1989. 7. Crow JF, Kimura, Properties of a finite population. In: An introduction to population genetics theory. The Blackburn Press, Caldwell, New Jersey, 1970.
24	Assesment

TERM LEARNING ACTIVITIES	NUMBER	PERCENT
Midterm Exam	1	30
Quiz	2	10
Homeworks, Performances	0	0
Final Exam	1	60
Total	4	100
Contribution of Term (Year) Learning Activities to Success Grade		40
Contribution of Final Exam to Success Grade		60
Total		100
Measurement and Evaluation Techniques Used in the Course	Classical (written) exams
Information	It is expected to answer the questions to be asked about the basic subjects given in the course at a level that can get the base score specified in the regulation.

ECTS / WORK LOAD TABLE

CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS

LO: Learning Objectives

PQ: Program Qualifications

Contribution Level:

1 Very Low

2 Low

3 Medium

4 High

5 Very High