To give general information about the molecular mechanisms of the intracellular molecular signaling and cell communication system, to teach the molecular mechanisms of diseases caused by cell signaling disorders, to gain basic knowledge that can be linked to other pre-clinical courses, to enable and facilitate the clinical approach
20
Contribution of the Course to Professional Development
Understanding the molecular mechanisms of intracellular and intercellular communication
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Learning Outcomes:
1
Understanding the molecular mechanisms of intracellular and intercellular communication;
2
Learning cell signal transduction defects and their molecular bases;
3
Having knowledge about diseases related to cell signal transduction disorders;
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Course Content:
Week
Theoretical
Practical
1
Introduction to cell signaling
2
Basic mechanisms of intercellular communication
3
General structure and properties of cell receptors
4
Nuclear receptors and related diseases
5
Ion-coupled receptors and related diseases
6
G protein-coupled receptors and related diseases
7
Enzym-coupled cell surface receptors
8
Tyrosine kinase activation and related diseases
9
Serine / threonine kinase activation and related diseases
10
Secondary messengers: cytoplasmic signal transduction and signal cascades
11
Secondary messengers: cytoplasmic signal transduction and signal cascades
12
Cytoplasmic signaling disorders and clinical effects
13
Significant signals in organism development
14
Extracellular matrix (ECM) and signal transduction related diseases
23
Textbooks, References and/or Other Materials:
Molecular Biology of the Cell, Alberts, Garland Science, Molecular Cell Biology, Lodish, WH Freeman and Company, The Cell: A molecular Approach , Geoffrey M. Copper
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Assesment
TERM LEARNING ACTIVITIES
NUMBER
PERCENT
Midterm Exam
1
40
Quiz
0
0
Homeworks, Performances
0
0
Final Exam
1
60
Total
2
100
Contribution of Term (Year) Learning Activities to Success Grade
40
Contribution of Final Exam to Success Grade
60
Total
100
Measurement and Evaluation Techniques Used in the Course
80% attendance is required.
Information
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ECTS / WORK LOAD TABLE
Activites
NUMBER
TIME [Hour]
Total WorkLoad [Hour]
Theoretical
14
1
14
Practicals/Labs
0
0
0
Self Study and Preparation
14
4
56
Homeworks, Performances
0
0
0
Projects
0
0
0
Field Studies
0
0
0
Midtermexams
1
10
10
Others
0
0
0
Final Exams
1
10
10
Total WorkLoad
90
Total workload/ 30 hr
3
ECTS Credit of the Course
3
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CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
