To understand the structure, organization and control mechanisms of gene expression in eukaryotic genes.
20
Contribution of the Course to Professional Development
21
Learning Outcomes:
1
Knows kromatin structure and organisation in eukaryotes.;
2
Knows gene structure and organisation in eukaryotes.;
3
Knows control mechanisms in gene clusters in eukaryotes.;
4
Knows the effects of cellular and environmental signals on gene expresion in eukaryotes.;
5
Knows how to analyze current data on eukaryotic gene expression by means of bioinformatic tools.;
22
Course Content:
Week
Theoretical
Practical
1
Genome organization and genome analysis methods in eukaryotes.
2
Structure and organization of eukaryotic kromatins, histone modifications.
3
Control mechanisms of DNA replication
4
RNA polymerases, control mechanisms of transcription.
5
RNA processing
6
Post transcriptional regulation
7
Control mechanisms by RNA localization and stability.
8
Repeating courses and midterm exam
9
Genetic code, translation initiation in eukaryotes.
10
Translational regfulation .
11
Homework. Discussion of homework and presentation, assignments of topics.
12
DNA repair in eukaryotes, .
13
Genome structure and regulation of organel genes
14
Maternal genes and omic studies
23
Textbooks, References and/or Other Materials:
1. B. Lewin. Genes IX. Jones and Bartlett Publishers. 2.. Selected articles from Cell., Science., Molecular and Cellular Biology, Eukaryotic Cell journals.
24
Assesment
TERM LEARNING ACTIVITIES
NUMBER
PERCENT
Midterm Exam
1
25
Quiz
0
0
Homeworks, Performances
1
25
Final Exam
1
50
Total
3
100
Contribution of Term (Year) Learning Activities to Success Grade
50
Contribution of Final Exam to Success Grade
50
Total
100
Measurement and Evaluation Techniques Used in the Course
Information
25
ECTS / WORK LOAD TABLE
Activites
NUMBER
TIME [Hour]
Total WorkLoad [Hour]
Theoretical
14
3
42
Practicals/Labs
0
0
0
Self Study and Preparation
14
4
56
Homeworks, Performances
1
27
27
Projects
0
0
0
Field Studies
0
0
0
Midtermexams
1
25
25
Others
0
0
0
Final Exams
1
30
30
Total WorkLoad
180
Total workload/ 30 hr
6
ECTS Credit of the Course
6
26
CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
