1 |
Course Title: |
CARBONION CHEMISTRY |
2 |
Course Code: |
KIM4011 |
3 |
Type of Course: |
Optional |
4 |
Level of Course: |
First Cycle |
5 |
Year of Study: |
4 |
6 |
Semester: |
7 |
7 |
ECTS Credits Allocated: |
5 |
8 |
Theoretical (hour/week): |
3 |
9 |
Practice (hour/week) : |
0 |
10 |
Laboratory (hour/week) : |
0 |
11 |
Prerequisites: |
None |
12 |
Recommended optional programme components: |
None |
13 |
Language: |
Turkish |
14 |
Mode of Delivery: |
Face to face |
15 |
Course Coordinator: |
Doç.Dr. NEVİN ARIKAN ÖLMEZ |
16 |
Course Lecturers: |
Prof. Dr. Necdet Coşkun Prof. Dr. Mustafa Tavaslı |
17 |
Contactinformation of the Course Coordinator: |
narikan@uludag.edu.tr +90 224 29 41 731 Uludağ Üniversitesi, Fen-Edebiyat Fakültesi, Kimya Bölümü, 16059 Görükle / BURSA, |
18 |
Website: |
|
19 |
Objective of the Course: |
The aim of the course is to provide information about properties, synthesis, reactions and applications of carbonyl compounds and derivatives, amines and phenols. |
20 |
Contribution of the Course to Professional Development |
|
Week |
Theoretical |
Practical |
1 |
Carboxyclic acids
Description and general properties, synthesis and reactions of carboxyclic acids. Classification of the carboxyclic acid derivatives (acid chloride, ester, acid anhydride, amide, nitrile compounds).
Efficiency range of carboxyclic acid derivatives |
|
2 |
Acid chlorides and Anhydrides
Description, nomenclature, and general properties, synthesis and reactions of acid chlorides
Description, nomenclature and general properties, synthesis and reactions of acid anhydrides |
|
3 |
Esters
Description, nomenclature, and general properties, synthesis and reactions of esters
Hydrolysis reaction of esters in acidic and basic mediums. Synthesis of cyclic ester compounds (lactone) |
|
4 |
Amides
Description, nomenclature, and general properties , base properties, synthesis and reactions of amides. Reduction of amides.
Synthesis of cyclic amide compounds |
|
5 |
Nitriles
Description, nomenclature, and general properties, synthesis and reactions of nitriles. Synthesis of carboxylic acid from nitrile compounds |
|
6 |
Conjugated diene systems
Description and general properties of conjugated diene systems. Stability of conjugated dienes. Description of MO. 1,2 and 1,4- additions to conjugated diene systems. 1,4 cycloaddition reactions of conjugated dienes (Diels-Alder reaction and its general principles) |
|
7 |
Carbonyl Alpha-Substitution Reaction
Keto-Enole tautomerism: Formation of enole and enolate. Stability of the enolate structures. Acidity of alpha-hydrogens
Reactions of Enoles: Alpha-halogenation of Aldehydes and ketone. Alpha-bromination of carboxylic acids |
|
8 |
Problem solving
Midterm Exam
|
|
9 |
Reactions of Enolate Ions: Alkylation of enolate ion. Halogenation of enolate ion. Selenization of enolat ion |
|
10 |
Carbonyl Condensation Reactions
Aldole condensation reaction-between Aldehyde and ketones. Claisen condensation reaction-between esters. Knoevenagel condensation reaction-between diethyl malonate/Malononitrile and Aldehyde/Ketone |
|
11 |
Phenol, Aniline and Aryl halogenides
Electrophilic aromatic substitution reactions. Nucleophilic aromatic substitution reactions. Acid-base reactions |
|
12 |
Aliphatic Amines
Nomenclature and physical properties
Basicity of amines. Synthesis of Amines. |
|
13 |
Reactions of amines |
|
14 |
Polycyclic and Heterocyclic Compounds
Samples and applications to polycyclic and heterocyclic compounds.
Reactions and synthesis methods of polycyclic and hetrocyclic compounds |
|
23 |
Textbooks, References and/or Other Materials: |
1) G. Solomons ve C. Fryhle (Çev. Ed. G. Okay ve Y. Yıldırır), Organik Kimya, Literatür Yayınları, 2002. 2) R. J. Fessenden ve J. S. Fessenden (Çev. Ed. T. Uyar), Organik Kimya, Güneş Kitabevi, 1992. 3) J. McMurry, Organic Chemistry, Brooks/Cole Publishing Comp., 1992. 4) P. Y. Bruice, Organic Chemistry, Prentice Hall, 2001. |
24 |
Assesment |
|