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COURSE SYLLABUS
ADVANCED HETEROCYCLIC CHEMISTRY
1 Course Title: ADVANCED HETEROCYCLIC CHEMISTRY
2 Course Code: KIM5055
3 Type of Course: Optional
4 Level of Course: Third Cycle
5 Year of Study: 1
6 Semester: 1
7 ECTS Credits Allocated: 6
8 Theoretical (hour/week): 3
9 Practice (hour/week) : 0
10 Laboratory (hour/week) : 0
11 Prerequisites: Organic Chemistry I and II courses
12 Recommended optional programme components: None
13 Language: Turkish
14 Mode of Delivery: Face to face
15 Course Coordinator: Prof. Dr. GANİ KOZA
16 Course Lecturers: Prof. Dr. Necdet COŞKUN
Doç. Dr. Nevin ARIKAN ÖLMEZ
Dr. Öğr. Üyesi Meliha ÇETİN KORUKÇU
17 Contactinformation of the Course Coordinator: ganikoza@uludag.edu.tr
+90 224 27 55 083
Uludağ Üniversitesi, Fen-Edebiyat Fakültesi, Kimya Bölümü, 16059 Görükle / BURSA, TÜRKİYE
18 Website:
19 Objective of the Course: The aim of this course is to introduce heterocyclic compounds which are one of the basic groups of organic chemistry. To teach the synthesis and reactions of heterocyclic structures and their biological activities.
20 Contribution of the Course to Professional Development Recognize the structures of heterocyclic compounds. Learns synthesis, reactions and biological activities of these structures.
21 Learning Outcomes:
1 The student will recognize the heterocyclic compounds.;
2 The student will learn aromatic and non-aromatic heterocyclic compounds.;
3 The student will learn the structures of aromatic heterocyclic compounds.;
4 The student will learn the synthesis of aromatic heterocyclic compounds.;
5 The student will learn the reactions of aromatic heterocyclic compounds.;
6 The student will learn about bioactive heterocyclic compounds.;
22 Course Content:
Week Theoretical Practical
1 Three- and four-memberd non-aromatic heterocyclic compounds: nomenclature, structure, synthesis, reactions and medicinal uses
2 Five- and six-memberd non-aromatic heterocyclic compounds: nomenclature, structure, synthesis, reactions and medicinal uses
3 Pyrrole, Furan and Thiophene: structure, synthesis, reactions and medicinal uses
4 Imidazole, Oxazole and Thiazole: structure, synthesis, reactions and medicinal uses
5 Pyrazole, Isoxazole and Isothiazole: structure, synthesis, reactions and medicinal uses
6 Indole: structure, synthesis, reactions and medicinal uses
7 Benzofuran and Benzothiophene: structure, synthesis, reactions and medicinal uses
8 Pyridine, Quinoline and Isoquinoline: structure, synthesis, reactions and medicinal uses
9 Purine and Pyrimidine: structure, synthesis, reactions and medicinal uses
10 Triazine and Tetrazine: structure, synthesis, reactions and medicinal uses
11 Acridine and Coumarin: structure, synthesis, reactions and medicinal uses
12 Azepine and Benzodiazepine: structure, synthesis, reactions and medicinal uses
13 Spiro heterocyclic compounds: structure, synthesis, reactions and medicinal uses
14 Poly heterocyclic compounds: structure, synthesis, reactions and medicinal uses
23 Textbooks, References and/or Other Materials: 1) Progress in Heterocyclic Chemistry, Book Series, Elsevier 1989-2021
2) Fundamentals Of Heterocyclic Chemistry, Louis D. Quin, John A. Tyrell, Wiley 2010
3) Modern Heterocyclic Chemistry, Julio Alvarez-Builla, Juan Jose Vaquero, and José Barluenga, Wiley 2011
4) Heterocyclic Chemistry, Malcolm Sainsbury, The Royal Society of Chemistry 2001
24 Assesment
TERM LEARNING ACTIVITIES NUMBER PERCENT
Midterm Exam 1 20
Quiz 0 0
Homeworks, Performances 1 20
Final Exam 1 60
Total 3 100
Contribution of Term (Year) Learning Activities to Success Grade 40
Contribution of Final Exam to Success Grade 60
Total 100
Measurement and Evaluation Techniques Used in the Course Homeworks and written exams
Information
25 ECTS / WORK LOAD TABLE
Activites NUMBER TIME [Hour] Total WorkLoad [Hour]
Theoretical 14 3 42
Practicals/Labs 0 0 0
Self Study and Preparation 14 3 42
Homeworks, Performances 1 8 48
Projects 0 0 0
Field Studies 0 0 0
Midtermexams 1 23 23
Others 0 0 0
Final Exams 1 25 25
Total WorkLoad 180
Total workload/ 30 hr 6
ECTS Credit of the Course 6
26 CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
PQ1 PQ2 PQ3 PQ4 PQ5 PQ6 PQ7 PQ8 PQ9 PQ10
LO1 5 4 5 4 4 3 4 4 5 3
LO2 5 4 5 4 4 3 4 4 5 3
LO3 5 4 4 4 4 3 5 4 5 4
LO4 4 4 3 4 5 3 4 4 4 4
LO5 4 5 3 4 5 3 4 4 4 4
LO6 4 5 3 4 5 3 4 4 4 4
LO: Learning Objectives PQ: Program Qualifications
Contribution Level: 1 Very Low 2 Low 3 Medium 4 High 5 Very High
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