None
However, it is strongly recommended that students should have read Organic Chemistry I and Organic Chemistry II.
12
Recommended optional programme components:
None
13
Language:
Turkish
14
Mode of Delivery:
Face to face
15
Course Coordinator:
Doç.Dr. NEVİN ARIKAN ÖLMEZ
16
Course Lecturers:
Prof. Dr. Necdet COŞKUN Prof. Dr. Mustafa TAVASLI
17
Contactinformation of the Course Coordinator:
narikan@uludag.edu.tr +90 224 29 41731 Uludag University Faculty of Sciences and Arts Department of Chemistry 16059 Gorukle / BURSA
18
Website:
19
Objective of the Course:
The aim of this course is to explain the basic principles and differences of the most used modern mass spectrometry techniques and to determine the structures of organic compounds using the mass spectrum
20
Contribution of the Course to Professional Development
To learn the basic principles and differences of the most used modern mass spectrometry techniques.
21
Learning Outcomes:
1
Knowing the basic aspects of mass spectrometry;
2
Learning the working principle of mass spectrometer.;
3
Knowing the modern mass spectrometry techniques and application areas;
4
Learning the determination of structures of organic compounds with Mass spectrum;
22
Course Content:
Week
Theoretical
Practical
1
Introduction, Principles Diagram of a Mass Spectrometer, History, Application areas of mass spectrometry.
2
Calculation of molecular masses, mass units.
3
Mass Spectrometer
4
Ionization techniques; Formation and Fragmentation of Ions.
5
Mass Analysers ; Quadrupole Analysers Ion Trap Analysers ,The Electrostatic Trap or ‘Orbitrap’, Time-of-Flight Analysers , Magnetic and Electromagnetic Analysers, Ion Cyclotron Resonance and Fourier Transform Mass Spectrometry , Hybrid Instruments.
6
Detectors and Computers
7
Mass spectrum and peak types: Molecular ion peak, Isotopic peaks, Peaks of molecular fragments, ion-molecule peaks, Double charged ion peaks, Semi-stable peaks.
8
Problem solving
9
Types of molecular fragmentation
10
Molecular fragmentation according to functional group
11
Mass spectrum, structure determination
12
Mass spectrum, structure determination
13
Other mass spectrometry techniques
14
Problem Solving
23
Textbooks, References and/or Other Materials:
Edmond De Hoffmann & Vincent Stroobant, Mass Spectrometry: Principles and Applications,, 3rd ed., John Wiley, 2007 -Jürgen H Gross, Mass Spectrometry: A Textbook, 2nd ed., Springer-Verlag, 2011. -J.Throck Watson & O. David Sparkman, Introduction to Mass Spectrometry: Instrumentation, Applications, and Strategies for Data Interpretation, 4th ed., John Wiley, 2007. -Ender Erdik, Organik Kimyada Spektroskopik Yöntemler
24
Assesment
TERM LEARNING ACTIVITIES
NUMBER
PERCENT
Midterm Exam
1
40
Quiz
0
0
Homeworks, Performances
0
0
Final Exam
1
60
Total
2
100
Contribution of Term (Year) Learning Activities to Success Grade
40
Contribution of Final Exam to Success Grade
60
Total
100
Measurement and Evaluation Techniques Used in the Course
It is evaluated by midterm exam, and final exam, which consists of classical questions, and homework.
Information
25
ECTS / WORK LOAD TABLE
Activites
NUMBER
TIME [Hour]
Total WorkLoad [Hour]
Theoretical
14
3
42
Practicals/Labs
0
0
0
Self Study and Preparation
13
1
13
Homeworks, Performances
0
0
0
Projects
0
0
0
Field Studies
0
0
0
Midtermexams
1
48
48
Others
0
0
0
Final Exams
1
48
48
Total WorkLoad
151
Total workload/ 30 hr
5,03
ECTS Credit of the Course
5
26
CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
