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Course Title: |
ORGANIC CHEMISTRY II |
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Course Code: |
KIM2012 |
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Type of Course: |
Compulsory |
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Level of Course: |
First Cycle |
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Year of Study: |
2 |
6 |
Semester: |
4 |
7 |
ECTS Credits Allocated: |
4 |
8 |
Theoretical (hour/week): |
4 |
9 |
Practice (hour/week) : |
0 |
10 |
Laboratory (hour/week) : |
0 |
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Prerequisites: |
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Recommended optional programme components: |
None |
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Language: |
Turkish |
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Mode of Delivery: |
Face to face |
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Course Coordinator: |
Prof. Dr. MUSTAFA TAVASLI |
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Course Lecturers: |
Prof. Dr. NECDET COŞKUN |
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Contactinformation of the Course Coordinator: |
mtavasli@uludag.edu.tr +90 224 29 41 732 Uludağ Üniversitesi, Fen-Edebiyat Fakültesi, Kimya Bölümü, 16059 Görükle / BURSA, TÜRKİYE |
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Website: |
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Objective of the Course: |
To introduce some fundemantal organic molecules and to discuss their synthesis and reactions. |
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Contribution of the Course to Professional Development |
To apply some fundemöantal knowledge in industry and producttion facilities. |
Week |
Theoretical |
Practical |
1 |
Ethers and Epoxides
• Classification-Symmetric and Asymmetric
• Physical properties and Dipole-Dipole Interactions
• Nomenclature
• Syntheses
? Dehydration of Alcohols
? Williamson Ether Synthesis
? Addition of alcoxymercury-mercury elimination to alkenes
? Hydroxyboration of alkenes oxidation
• Reactions:
Breaking up with HI
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Epoxides
? Nomenclature
? Syntheses
? Reactions
Alkenes I: Properties and Preparation
• Nomenclature with (E)/(Z) System
• Relative Stability of Alkenes Sycloalkenes
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• Syntheses of Alkenes: Elimination reactions over (E1/E2).
? From alkylhalides
? From alcohols
Stability of carbocation and Molecular Rearrangements
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Alkenes II: Electrophilic Addition Reactions
? Addition of Hidrogenhalides (Markovnikov Rule)
? Addition of sulphuric acid
? Addition of water
? Addition of Bromine / Chlorine |
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? Formation of Halohydrin
? Hydroboration
? Oxymercury Addition
? Carben Addition
? Oxidation
? Reduction |
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Alkines
Nomenclature
The acidity of terminal alkynes and Nucleophilicity
• Syntheses:
From Elimination (E1/E2) Reactions
• Reactions:
? Bromine / Chlorine Addition
? Hydrogenhalide Addition
? HgSO4 catalised Hydration
? Hydroboration
? Reduction
? Oxidation |
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Nuclear Magnetic Resonance Spectrometer
? Nuclear Spin: The source of the signal (Shielding / Deshielding)
? Chemical shift (Equivalent / Nonequivalent Protons)
? Signal Splitting (Spin-Spin Coupling)
Proton NMR Spektrums and Rate İşlemleri
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Benzene and Aromaticity
? Nomenclature of benzene derivatives
? The structure and stability of benzene
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? Aromaticity and Hückel Rule
? Aromatic Ions
? Benzenoid Aromatic Compounds
? Heterocyclic Aromatic Compounds
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Electophilic Aromatic Substitution Reactions
• Genelal Mechanism: Arenium Ions
? Halogenation of Benzene
? Nitration of Benzene |
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? Sulphonation of Benzene
? Alkyllation of Benzene - Friedel-Crafts
? Acylation of Benzene - Friedel-Crafts
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Aldehides and Ketones: Nucleophilic Addition Reactions to Carbonyl Group
• Nomenclature
• Physical Properties
• Syntheses
? From oxidation of Alcohols
? From breaking up alkenes with ozone
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? Reactions: Nucleophilic Addition Reactions to Carbonyl Group
? Addition of Alcohols
? Addition of Ammonia and Derivatives
? Addition of Hydrogencyanide |
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? Addition of Ylides (Wittig Reaction)
? Addition of Organometallic Reagents (Reformatsky Reaction)
? Reduction
? Oxidation |
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