1	Course Title:	CELLULAR AND MOLECULAR BASICS OF INFLAMMATION
2	Course Code:	TMİ6007
3	Type of Course:	Optional
4	Level of Course:	Third Cycle
5	Year of Study:	1
6	Semester:	1
7	ECTS Credits Allocated:	3
8	Theoretical (hour/week):	1
9	Practice (hour/week) :	0
10	Laboratory (hour/week) :	0
11	Prerequisites:	NONE
12	Recommended optional programme components:	None
13	Language:	Turkish
14	Mode of Delivery:	Face to face
15	Course Coordinator:	Prof. Dr. BARBAROS ORAL
16	Course Lecturers:	-
17	Contactinformation of the Course Coordinator:	Bursa Uludağ Üniversitesi, Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, İmmünoloji Bilim Dalı, 16059, Nilüfer, BURSA E-mail: oralb@uludag.edu.tr Phone: 2954114
18	Website:
19	Objective of the Course:	This course is aimed to provide the student to comprehend the immunological mechanisms involved in the process of inflammation, benefits of inflammatory responses and the roles of an excessive inflammatory response for the pathogenesis of various diseases.
20	Contribution of the Course to Professional Development

21

Learning Outcomes:

1 To comprehend the immunological mechanisms involved in the process of inflammation; 2 To gain some basic immunological information about how inflammation functions as an innate immune defense mechanism; 3 To acquire knowledge about the benefits associated with the inflammatory response; 4 To comprehend how an excessive inflammatory response can be harmful to the body;

22	Course Content:

Week	Theoretical	Practical
1	Inflammatory cells and characteristics
2	Pro-inflammatory and anti-inflammatory cytokines
3	Chemokines
4	Vascular endothelium and characteristics
5	Endothelial cell activation and NF-kB
6	Reactive oxygen and nitrogen methabolisms
7	Acute inflammation
8	Chronic inflammation
9	Rheumatoid arthritis
10	Behçet’s Disease
11	Vasculitis
12	Atherosclerosis
13	Chronic inflammation and cancer
14	Anti-inflammatory drugs and their effects

23	Textbooks, References and/or Other Materials:	1. Abbas A.K., Lichtman A.H., Pillai S.”Cellular and Molecular Immunology”, Elsevier Saunders Elsevier, 8th edition (2012). 2. Rich R.R., Fleisher T.A., Shearer W.T., Kotzin B.L., Schroeder Jr H.W., “Clinical Immunology: Principles and Practice”, Mosby International Ltd., 3rd edition (2008). 3. Kılıçturgay K., “İmmünoloji”, Nobel & Güneş Tıp Kitabevi, 3. Baskı (2003). 4. Stevens C.D., "Clinical Immunology & Serology: Laboratory Perspective", E.A. Davis Company, 3rd edition (2010).
24	Assesment

TERM LEARNING ACTIVITIES	NUMBER	PERCENT
Midterm Exam	0	0
Quiz	0	0
Homeworks, Performances	5	50
Final Exam	1	50
Total	6	100
Contribution of Term (Year) Learning Activities to Success Grade		50
Contribution of Final Exam to Success Grade		50
Total		100
Measurement and Evaluation Techniques Used in the Course	Measurement and evaluation are performed according to the Rules & Regulations of Bursa Uludağ University on Undergraduate Education.
Information

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ECTS / WORK LOAD TABLE

Activites	NUMBER	TIME [Hour]	Total WorkLoad [Hour]
Theoretical	14	1	14
Practicals/Labs	0	0	0
Self Study and Preparation	14	2	28
Homeworks, Performances	5	10	50
Projects	0	0	0
Field Studies	0	0	0
Midtermexams	0	0	0
Others	0	0	0
Final Exams	1	2	2
Total WorkLoad			94
Total workload/ 30 hr			3,13
ECTS Credit of the Course			3

26	CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
PQ1 PQ2 PQ3 PQ4 PQ5 PQ6 PQ7 PQ8 PQ9 PQ10 PQ11 PQ12 LO1 5 5 5 0 0 0 2 0 0 0 0 0 LO2 5 5 5 0 0 0 2 0 0 0 0 0 LO3 5 5 5 0 0 0 2 0 0 0 0 0 LO4 0 0 0 0 0 0 0 0 0 0 0 0

LO: Learning Objectives

PQ: Program Qualifications

Contribution Level:

1 Very Low

2 Low

3 Medium

4 High

5 Very High