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COURSE SYLLABUS
ORGANIC CHEMISTRY
1 Course Title: ORGANIC CHEMISTRY
2 Course Code: KIM2433
3 Type of Course: Compulsory
4 Level of Course: First Cycle
5 Year of Study: 2
6 Semester: 3
7 ECTS Credits Allocated: 4
8 Theoretical (hour/week): 3
9 Practice (hour/week) : 0
10 Laboratory (hour/week) : 0
11 Prerequisites: None
12 Recommended optional programme components: None
13 Language: Turkish
14 Mode of Delivery: Face to face
15 Course Coordinator: Doç. Dr. AYHAN YILDIRIM
16 Course Lecturers:
17 Contactinformation of the Course Coordinator: Prof. Dr. Ayhan YILDIRIM
yildirim@uludag.edu.tr
0 224 29 41 771
18 Website:
19 Objective of the Course: The aim of the course is to teach the basic concepts and topics in organic chemistry, to develop the students' ability to solve organic chemistry problems and to enable students to develop their ability to use organic chemistry in molecular biology and genetics studies.
20 Contribution of the Course to Professional Development
21 Learning Outcomes:
1 Learning basic organic chemistry terms;
2 Comprehending the general properties of organic compounds;
3 Learning stereochemistry and three dimensional structures of organic and biomolecules and drawing related structures;
4 Writing organic reactions and their mechanisms;
22 Course Content:
Week Theoretical Practical
1 Chemical bonds and molecular structures The importance of organic chemistry, chemical bond types, Lewis structures, formal load, VBT, MOT, hybridization, VSEPR
2 Functional groups, molecular formulas, intermolecular forces, resonance Dipole moment, molecular polarity, intermolecular forces, H-bond and its effects, London distribution forces, representations of organic molecules, line bonds, compacted formulas, three dimensional structures, functional groups, resonance
3 Organic acids and bases Acid-base definitions, curve arrows, Ka and pKa constants of organic acids, stabilization of anions in organic acids, ARIO (atom, resonance, inductive effect, otbital)
4 Alkanes and cycloalkanes Nomenclature of alkanes and cycloalkanes, special and systematic nomenclature, IUPAC rules, bicyclic structures, structure isomers, functional group isomers, sources and use of alkanes, properties, combustion reactions, Newman projection, free radical reactions
5 Conformation analysis and stereochemistry Conformational analysis of ethane, propane and butane, conformations in cycloalkanes, cis-trans isomerism in ring structures, stereoisomerism, chirality, chiral centers, enantiomers, diastereomers, Cahn-Ingold-Prelog system
6 Alkenes, structures, syntheses and reactions Natural compounds containing double bonds, properties and nomenclature of alkenes, industrial synthesis methods, stereoisomers in alkenes, stability in alkenes, elimination reactions, E1 and E2 mechanisms
7 Addition reactions to alkenes Hydrohalogenation, Markovnikov rule, carbocation cycles, hydration, oxymercuration-demercuration, hydroboration-oxidation, catalytic hydrogenation, halogenation, syn- and anti-dihydroxylation, oxidative bond cleavage
8 Substitution reactions Alkyl halides, SN2 and SN1 mechanisms, Substitution reactions in biological systems
9 Alcohols, ethers, epoxides, thiols Properties of alcohols, ethers, epoxides and thiols, their properties and nomenclature, usage areas, synthesis methods, reactions, spectroscopic properties
10 Aldehydes and ketones Natural compounds containing aldehyde and ketone groups, structure and properties of aldehydes and ketones, nomenclature, synthesis methods, reactions, Wittig reaction, spectroscopic properties
11 Aromatic compounds Benzene structure, nomenclature, aromaticity, Hückel rule, MOT and Frost rings, aromatic heterocyclic compounds, benzylic reactions, other reactions of aromatic compounds, spectroscopic properties
12 Carboxylic acids and their derivatives Carboxyl groups in natural compounds, structure and properties, acidity, nomenclature, synthesis and reactions, esters, anhydrides, amides, nitriles, spectroscopic properties
13 IR, 1H NMR and 13C NMR, UV-VIS spectroscopic methods, GC-MS IR spectroscopy and organic structure analysis, 1H NMR and 13C NMR spectroscopy and organic structure analysis, UV-VIS spectroscopy and organic structure analysis, GC-MS specrometry and organic structure analysis
14 Organic chemistry of biomolecules Carbohydrates, proteins, lipids, nucleic acids, structural properties and some reactions
23 Textbooks, References and/or Other Materials: G. Solomons and C. Fryhle (Ed. G. Okay and Y. Yıldırır), Organik Kimya, Literatür Yayınları, 2002.
J. McMurry, Organic Chemistry, Brooks/Cole Publishing Comp., 1992.
P. Y. Bruice, Organic Chemistry, Prentice Hall, 2001.
R. J. Fessenden and J. S. Fessenden (Ed. T. Uyar), Organik Kimya, Güneş Kitabevi, 1992.
24 Assesment
TERM LEARNING ACTIVITIES NUMBER PERCENT
Midterm Exam 1 40
Quiz 0 0
Homeworks, Performances 0 0
Final Exam 1 60
Total 2 100
Contribution of Term (Year) Learning Activities to Success Grade 40
Contribution of Final Exam to Success Grade 60
Total 100
Measurement and Evaluation Techniques Used in the Course
Information
25 ECTS / WORK LOAD TABLE
Activites NUMBER TIME [Hour] Total WorkLoad [Hour]
Theoretical 14 3 42
Practicals/Labs 0 0 0
Self Study and Preparation 14 3 42
Homeworks, Performances 0 0 0
Projects 0 0 0
Field Studies 0 0 0
Midtermexams 1 12 12
Others 0 0 0
Final Exams 1 24 24
Total WorkLoad 120
Total workload/ 30 hr 4
ECTS Credit of the Course 4
26 CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
PQ1 PQ2 PQ3 PQ4 PQ5 PQ6 PQ7 PQ8 PQ9 PQ10
LO1 0 0 3 0 0 0 0 0 0 0
LO2 0 0 3 0 0 0 0 0 0 0
LO3 0 0 4 0 3 0 0 0 0 0
LO4 0 0 0 0 0 0 0 0 0 3
LO: Learning Objectives PQ: Program Qualifications
Contribution Level: 1 Very Low 2 Low 3 Medium 4 High 5 Very High
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