1	Course Title:	DETERMINATION OF DRUG TOXICITY
2	Course Code:	VFR 6008
3	Type of Course:	Optional
4	Level of Course:	Third Cycle
5	Year of Study:	1
6	Semester:	2
7	ECTS Credits Allocated:	3
8	Theoretical (hour/week):	1
9	Practice (hour/week) :	2
10	Laboratory (hour/week) :	0
11	Prerequisites:	Determination of drug toxicity
12	Recommended optional programme components:	None
13	Language:	Turkish
14	Mode of Delivery:	Face to face
15	Course Coordinator:	Prof. Dr. HASAN HÜSEYIN ORUÇ
16	Course Lecturers:	Doç. Dr. H. Hüseyin ORUÇ
17	Contactinformation of the Course Coordinator:	oruc@uludag.edu.tr +90 224 2941321 Veteriner Fakültesi Farmakoloji ve Toksikoloji Anabilim Dalı 16059 Bursa
18	Website:
19	Objective of the Course:	To educate qualified postgraduate students in the field of drug toxicities, types of toxicity, practise in laboratory animals.
20	Contribution of the Course to Professional Development

21

Learning Outcomes:

1 To comprehend of toxicity of drugs and importance; 2 To understand approach of laboratory animals; 3 To comprehend differences among to toxicity types; 4 To plan according to toxicity study aim; 5 To know specific conditions during toxicity studies; 6 To interpret the toxicity study results;

22	Course Content:

Week	Theoretical	Practical
1	Drug toxicity and importance	Introduction of toxicology laboratory
2	Toxicity, toxicity category	Introduction of instrument and equipments used in toxicology laboratory
3	Aim and target of toxicity tests	Introduction of instrument and equipments used in toxicology laboratory
4	Laboratory animals used in toxicity studies	Visiting to laboratory animal centre
5	Toxicity tests	Visiting to laboratory animal centre
6	Toxicity tests	Ethical rules and importance
7	Plan of toxicity studies	Make a plan for toxicology studies
8	Good laboratory practise in toxicology laboratories	Toxicity studies using some drugs on laboratory animals
9	Determination lethal doses of some drugs	Toxicity studies using some drugs on laboratory animals
10	Determination lethal doses of some drugs	Determination of LD50
11	Determination of toxicity and risk assesment	Determination of LD50
12	Specific conditions during toxicity studies	Risk assesment in toxicity studies
13	Assesment of toxicity test results	Risk assesment in toxicity studies
14	Assesment of toxicity test results	Assesment of practises

23	Textbooks, References and/or Other Materials:	Gupta, R.C. (Ed.). Veterinary Toxicology. Amsterdam, Elsevier, 2007. L. F. M. van Zutphen , V. Baumans , A. C. Beynen. Principles of laboratory animal science. Amsterdam : Elsevier, 2005. Course Handbook. III. Congress and workshop of clinical and experimental research. 18-20 May, 2000, Kayseri, Türkiye. Evaluation of certain food additives : fifty-ninth report of the Joint FAO/WHO Expert Committee on Food Additives. Geneva : World Health Organization, 2002. Domer F. R. Animal Experiments in Pharmacological Analysis. Charles C Thomas Publisher, USA, 1971.
24	Assesment

TERM LEARNING ACTIVITIES	NUMBER	PERCENT
Midterm Exam	0	0
Quiz	0	0
Homeworks, Performances	2	50
Final Exam	1	50
Total	3	100
Contribution of Term (Year) Learning Activities to Success Grade		50
Contribution of Final Exam to Success Grade		50
Total		100
Measurement and Evaluation Techniques Used in the Course
Information

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ECTS / WORK LOAD TABLE

Activites	NUMBER	TIME [Hour]	Total WorkLoad [Hour]
Theoretical	14	1	14
Practicals/Labs	14	2	28
Self Study and Preparation	0	0	0
Homeworks, Performances	2	14	28
Projects	0	0	0
Field Studies	0	0	0
Midtermexams	0	0	0
Others	0	0	0
Final Exams	1	20	20
Total WorkLoad			90
Total workload/ 30 hr			3
ECTS Credit of the Course			3

26	CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
PQ1 PQ2 PQ3 PQ4 PQ5 PQ6 PQ7 PQ8 PQ9 PQ10 PQ11 PQ12 LO1 4 3 3 3 3 3 3 2 3 4 4 4 LO2 3 3 3 3 3 3 2 2 2 3 3 3 LO3 3 4 3 4 3 2 4 3 3 4 4 3 LO4 4 5 4 4 4 3 3 3 3 4 4 4 LO5 4 5 4 4 4 2 3 3 3 4 4 4 LO6 4 5 4 4 4 3 3 3 4 4 4 4

LO: Learning Objectives

PQ: Program Qualifications

Contribution Level:

1 Very Low

2 Low

3 Medium

4 High

5 Very High