1	Course Title:	BASIC IMMUNOLOGY AND SEROLOGIC DIAGNOSTIC METHODS
2	Course Code:	VMK 6003
3	Type of Course:	Compulsory
4	Level of Course:	Third Cycle
5	Year of Study:	1
6	Semester:	1
7	ECTS Credits Allocated:	6
8	Theoretical (hour/week):	2
9	Practice (hour/week) :	2
10	Laboratory (hour/week) :	0
11	Prerequisites:	None
12	Recommended optional programme components:	None
13	Language:	Turkish
14	Mode of Delivery:	Face to face
15	Course Coordinator:	Prof. Dr. AYŞIN ŞEN
16	Course Lecturers:	Prof. Dr. Ayşin Şen
17	Contactinformation of the Course Coordinator:	aysins@uludag.edu.tr 0224 294 1292 Uludağ Üniversitesi Veteriner Fakültesi Hayvan Hastanesi Mikrobiyoloji Anabilim Dalı,Görükle/Nilüfer,BURSA
18	Website:	http://saglikbilimleri.uludag.edu.tr/
19	Objective of the Course:	To conceive the structure of immune system and its functions and the basic principles of immunology, to interpret the immune response to some cases (infections, vaccinations) in domestic animals, to gain experience about applying and interpretation of serological tests to diagnosis of diseases and survey of postvaccinal immunity.
20	Contribution of the Course to Professional Development

21

Learning Outcomes:

1 To be able to describe basic structure of immune system; 2 To be able to describe components of nonspecific immunity, to conceive and interpret the reactions of nonspecific immunity.; 3 To be able to conceive the basic functions of humoral immunity and its role on body defense.; 4 To be able to conceive the basic functions of cellular immunity and its role on body defense; 5 To be able to explain the immunological reactions to some diseases in domestic animals and to interpret the consequences of these reactions.; 6 To be able to interpret the basic mechanisms of reaction between antigens and antibodies, to be able to apply the serological test that based on this reaction; 7 To be able to evaluate and interpret the results of serological tests; 8 To be able to use the knowledge that gained in this course for other courses.;

22	Course Content:

Week	Theoretical	Practical
1	Description of immunology and serology and basic consept	To obtain blood, serum, plasma
2	Immune system cells	Diluents and their preparation
3	Immune system organs	Precipitation tests
4	Nonspecific immune response, its mechanisms and importance.	Agglutination tests
5	Phagocytosis and phagocytic cells	Washing red blood cells and preparing of red cells suspension
6	Antigens and their structural characteristics	Hemagglutination tests
7	Immunoglobulins, their structure and functions.	Hemagglutination inhibition tests
8	Cytokins and signal transfer between cells.	ELISA
9	Complement and its importance for immune response.	Immunofluorescent assay
10	MHC molecules and its importance for immune response.	Other primary binding tests
11	Antigen processing and presenting	Tertiary binding tests
12	Humoral immune response	Sensitivity and specifity in serological tests
13	Cellular immune response	Evaluation of serological tests and using in the field
14	General assessment	General assessment

23	Textbooks, References and/or Other Materials:	Tizard, I.R.; Veterinary Immunoolgy An Introduction, Sixth Edition, W.B. Saunders Elsevier, 2009 Hudson,L., Hay, F.C.; Practical Immunologoy, Third Edition, Blackwell Scientific Publication, 1989 Parham,P.; The Immune System, Second Edition, Garland Science, 2005. Playfair,J., Bancroft,G.; Infection and Immunity, Third Edition, Oxford Univ. Press, 2008. Pier, G.B., Lyczak, J.B., Wetzler, L.M.; Immunology, Infection and Immunity, ASM Press, 2004.
24	Assesment

TERM LEARNING ACTIVITIES	NUMBER	PERCENT
Midterm Exam	0	0
Quiz	0	0
Homeworks, Performances	7	30
Final Exam	1	70
Total	8	100
Contribution of Term (Year) Learning Activities to Success Grade		30
Contribution of Final Exam to Success Grade		70
Total		100
Measurement and Evaluation Techniques Used in the Course
Information

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ECTS / WORK LOAD TABLE

Activites	NUMBER	TIME [Hour]	Total WorkLoad [Hour]
Theoretical	14	2	28
Practicals/Labs	14	2	28
Self Study and Preparation	6	8	48
Homeworks, Performances	7	8	56
Projects	0	0	0
Field Studies	0	0	0
Midtermexams	0	0	0
Others	2	5	10
Final Exams	1	10	10
Total WorkLoad			180
Total workload/ 30 hr			6
ECTS Credit of the Course			6

26	CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
PQ1 PQ2 PQ3 PQ4 PQ5 PQ6 PQ7 PQ8 PQ9 PQ10 PQ11 PQ12 LO1 0 0 5 0 0 0 0 0 0 0 0 0 LO2 0 0 3 0 0 0 0 0 0 0 0 0 LO3 0 0 3 0 0 0 0 0 0 0 0 0 LO4 0 0 4 0 0 0 0 0 0 0 0 0 LO5 0 0 5 0 0 0 0 0 0 3 0 0 LO6 0 0 5 0 4 0 0 0 0 2 0 0 LO7 0 0 4 0 4 0 0 0 0 3 0 0 LO8 0 0 0 0 0 0 0 0 0 0 0 0

LO: Learning Objectives

PQ: Program Qualifications

Contribution Level:

1 Very Low

2 Low

3 Medium

4 High

5 Very High