1	Course Title:	VIROLOGY I
2	Course Code:	VET2030
3	Type of Course:	Compulsory
4	Level of Course:	First Cycle
5	Year of Study:	2
6	Semester:	4
7	ECTS Credits Allocated:	2
8	Theoretical (hour/week):	1
9	Practice (hour/week) :	0
10	Laboratory (hour/week) :	2
11	Prerequisites:	None
12	Recommended optional programme components:	None
13	Language:	Turkish
14	Mode of Delivery:	Face to face
15	Course Coordinator:	Prof. Dr. KADİR YEŞİLBAĞ
16	Course Lecturers:	Araş.Gör.Dr. Gizem Alpay
17	Contactinformation of the Course Coordinator:	kyesilbag@uludag.edu.tr ; 2941295, Uludağ Ün. Veteriner Fak. Viroloji AD, Görükle Bursa
18	Website:
19	Objective of the Course:	Giving knowlegdes on basic princeples of viruses, propagation of viruses in in vivo and in vitro systems, viral pathogenesis and diagnostic methods
20	Contribution of the Course to Professional Development

21

Learning Outcomes:

1 To learnd basic terms in virology; 2 to learn structure, specifications, and differences from other microorganism; 3 to learn the cultivation systems for viruses; 4 to learn persistent and zoonotic infections; 5 to learn classificaion and taksonomi of the viruses; 6 to learn diagnostic procedures in viral infections; 7 to learn control and prevention from viral infections;

22	Course Content:

Week	Theoretical	Practical
1	Introduction of the course materials, origin of viruses, Evaluation of virology and History of virology in Turkey	Introduction of the course materials and research laboratory, basic principles of virology laboratory
2	Properties of viruses, differences between other microorganisms	How to use laboratory equipments
3	Structure of viruses, components and functions, Stability of Viruses to Chemical and Physical Agents	Cell cultures, primer cell culture preparation
4	Virus Taxonomy and criterias, order of RNA and DNA virus clasification	Sampling for virological diagnosis
5	BSE, biology and general properties of prions, prion diseases, Virus and virino theories	Inoculum preparation from sample material (leukosite, serum)
6	Replication of viruses and stages, Transcription, translation, post-translation proceses, inhibition of viral replication (antiviral drugs), Viral interference and interferon	Inoculum preparation from sample material (Svab, tissue, gaita)
7	Mutation, genetic and non-genetic interreactions, evalution of viruses, influence of genetic alterations on to viral infections	Inoculation into cell cultures
8	Virus propagation and titration	Inoculation to experimental animal
9	Virus and host cell interreactions	Virus inoculation of embryonating chicken eggs (Chorioallontoic membrane, Allantoic cavity)
10	Epidemiology and trasmisson of viral infections	Virus inoculation of embryonating chicken eggs (Amniotic cavity, Yolk sac)
11	Phatogenesis of viral infections	Virus titration (diluation method)
12	General principles of viral disease detection, sampling for diagnosis, isolation and identification, Viral antigen detection (dELISA, IF, PLA, HA, RİA, LA)	Virus titration (Plaque and immunoplaque assay)
13	Methods for antiviral antibody detection (SNT, iELISA, IIF, AGID,KFT, Hİ, )	Virus neutralization assay
14	Methods for viral nucleic acid detection and principles for practice (PCR, Elektroforezis)	Hemagglutination and hemagglutination inhibition assay

23	Textbooks, References and/or Other Materials:	1. Genel Viroloji (2010), Prof.Dr.Kadir Yeşilbağ, Medipress yayınevi 2. Viroloji Laboratuvar Uygulamaları, Prof.Dr.Kadir Yeşilbağ, UÜ Vet Fak yayınları 3. Fields Virology (Knipe DM ve Howley PM, 2009, Lippincott Williams&Wilkins)
24	Assesment

TERM LEARNING ACTIVITIES	NUMBER	PERCENT
Midterm Exam	1	30
Quiz	1	10
Homeworks, Performances	0	0
Final Exam	1	60
Total	3	100
Contribution of Term (Year) Learning Activities to Success Grade		40
Contribution of Final Exam to Success Grade		60
Total		100
Measurement and Evaluation Techniques Used in the Course
Information

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ECTS / WORK LOAD TABLE

Activites	NUMBER	TIME [Hour]	Total WorkLoad [Hour]
Theoretical	14	1	14
Practicals/Labs	14	2	28
Self Study and Preparation	3	3	9
Homeworks, Performances	0	0	0
Projects	0	0	0
Field Studies	0	0	0
Midtermexams	1	1	1
Others	0	0	0
Final Exams	1	1	1
Total WorkLoad			54
Total workload/ 30 hr			1,77
ECTS Credit of the Course			2

26	CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
PQ1 PQ2 PQ3 PQ4 PQ5 PQ6 PQ7 PQ8 PQ9 PQ10 PQ11 PQ12 LO1 5 2 2 5 2 1 2 1 1 2 2 5 LO2 5 3 4 5 2 1 2 1 2 2 3 3 LO3 5 5 5 5 3 1 3 1 2 2 3 3 LO4 5 5 4 5 5 1 5 5 4 2 4 5 LO5 5 3 3 5 5 1 4 5 4 2 2 5 LO6 5 3 5 4 5 1 4 3 5 2 3 4 LO7 5 3 5 5 5 1 4 4 4 2 3 4

LO: Learning Objectives

PQ: Program Qualifications

Contribution Level:

1 Very Low

2 Low

3 Medium

4 High

5 Very High