The aim of the course is to make the students learn some of the databases and analysis programs. The goals are to teach some of tha databases in Molecular Biology and how to search data using these databases.
20
Contribution of the Course to Professional Development
21
Learning Outcomes:
1
Analyse and solve problems using an integrated multidisciplinary approach.
;
2
Integrate and evaluate critically information from various sources.
;
3
Plan, conduct and write a programme of original research.
;
4
Use modern information and communications technologies.
;
5
Critically evaluate scientific publications.
;
6
Communicate effectively through oral presentations
;
7
Devise molecular methodologies for problems
;
8
Transfer techniques and solutions from one discipline to another.
;
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Course Content:
Week
Theoretical
Practical
1
Introduction
2
DNA, RNA, Protein
3
Primer design, Tm calculation, GC content
4
How to Search Databases (FASTA, BLAST), NCBI, sequence formats
5
Alignment of the sequences (clustalW),
6
protein translator, protein search in NCBI
7
Restriction enzymes, restriction map
NEB cutter
8
Transcription, translation
9
Protein Localization, leader sequence, Transmembrane domain finder (TMHMM), signal peptide finder
10
Entrez, pubmed
11
Protein motifs, protein 3D, protein digestion
12
Biochemical pathways, Vecscreen
13
RNA folding Mfold, tRNA in Genome
14
Post translational modifications
23
Textbooks, References and/or Other Materials:
F. ERSOY, Computational Molecular Biology Lecture Notes;
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Assesment
TERM LEARNING ACTIVITIES
NUMBER
PERCENT
Midterm Exam
1
40
Quiz
0
0
Homeworks, Performances
0
0
Final Exam
1
60
Total
2
100
Contribution of Term (Year) Learning Activities to Success Grade
40
Contribution of Final Exam to Success Grade
60
Total
100
Measurement and Evaluation Techniques Used in the Course
Information
25
ECTS / WORK LOAD TABLE
Activites
NUMBER
TIME [Hour]
Total WorkLoad [Hour]
Theoretical
14
1
14
Practicals/Labs
14
2
28
Self Study and Preparation
0
0
0
Homeworks, Performances
0
0
0
Projects
0
0
0
Field Studies
0
0
0
Midtermexams
1
40
40
Others
0
0
0
Final Exams
1
40
40
Total WorkLoad
122
Total workload/ 30 hr
4,07
ECTS Credit of the Course
4
26
CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
