Prof.Dr. Mustafa Tavaslı Doç.Dr. Nevin Arıkan Ölmez
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Contactinformation of the Course Coordinator:
coskun@uludag.edu.tr +90 224 29 41 725 Uludağ Üniversitesi, Fen-Edebiyat Fakültesi, Kimya Bölümü, 16059 Görükle / BURSA, TÜRKİYE
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Website:
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Objective of the Course:
The aim of the course is to make sure students understand organic syntheses, isolation and characterization techniques.
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Contribution of the Course to Professional Development
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Learning Outcomes:
1
Learning the risks (personel and environmental) about organic compounds and use the compounds with this consciousness;
2
Beholding practical the general properties of some organic compounds;
3
Becoming conscious about organic synthesis;
4
Developing of the knowledge and experience about the isolation of the product after organic synthesis;
5
Earning the organic laboratory culture;
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Course Content:
Week
Theoretical
Practical
1
Introduction General information Safety rules
2
Crystallization
- Crystallization of salicylic acid from salicylic acid-sand mixture
. Quiz
3
Destillation
- Separating of ethyl acetate and 1-butanol liquids which mixed with each other via simple and fractional distillation techniques
. Quiz
4
Chemical active extraction
- Separating of the solid mixture consist of biphenyl, 3-nitroaniline and benzoic acid via chemical active extraction based on acid-base reactions
. Quiz
5
Isolation of caffeine from tea
- Isolation of caffeine from tea solvent via extraction method
- Preparation of caffeine-salicylate derivative for proving the accuracy of isolated caffeine
. Quiz
6
Column and thin layer chromatography
- Isolation of chlorophyl and ß-carotene from spinach via column chromatography
- Applying of the isolated chlorophyl and ß-carotene to thin layer chromatography for determination of Rf values
. Quiz
7
Synthesis of sulpha drugs (First week)
- Synthesis of p-Acetamidobenzenesulphonyl chloride
. Quiz
8
Synthesis of sulpha drugs (Second week)
- Synthesis of p-aminobenzenesulphonamide
. Quiz
9
Problem solving
Midterm exam
. Quiz
10
Luminole synthesis
- Synthesis of 5-aminopthalhydrazide from 3-nitropthalic acid
. Quiz
11
Indigo synthesis (First week)
- Synthesis of pthalimide and anthranilic acid
. Quiz
Indigo synthesis (Third week)
- Synthesis of indigo
. Quiz
14
Reduction of camphore
- Reduction of camphore to isoborneol via NaBH4
. Quiz
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Textbooks, References and/or Other Materials:
1) G. Solomons ve C. Fryhle ;(Çev. Ed. G. Okay ve Y. Yıldırır), Organik Kimya; Literatür Yayınları, 2002. 2) Kenneth L. Williamson ; Macroscale and Microscale Organic Experiments,; D.C. Healt and Company, 1989. 3) Brian S. Furniss, Antony J. Hannaford, Peter W.G. Smith, Austin R. Tatchell; Vogel’s Textbook of Practical Organic Chemistry,; Longman Scientific &Technical,; 1989. 4) Ender Erdik, Metin Obalı, Nadire Yüksekışık, Atilla Öktemer, Tarık Pekel, İhsanoğlu; Denel Organic Kimya; A.Ü.F.F Döner Sermaye İşletmesi yayınları, 2000.
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Assesment
TERM LEARNING ACTIVITIES
NUMBER
PERCENT
Midterm Exam
1
25
Quiz
1
25
Homeworks, Performances
0
0
Final Exam
1
50
Total
3
100
Contribution of Term (Year) Learning Activities to Success Grade
50
Contribution of Final Exam to Success Grade
50
Total
100
Measurement and Evaluation Techniques Used in the Course
Information
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ECTS / WORK LOAD TABLE
Activites
NUMBER
TIME [Hour]
Total WorkLoad [Hour]
Theoretical
0
0
0
Practicals/Labs
14
4
56
Self Study and Preparation
14
0,5
7
Homeworks, Performances
0
0
0
Projects
0
0
0
Field Studies
0
0
0
Midtermexams
1
24
24
Others
12
0,5
6
Final Exams
1
24
24
Total WorkLoad
117
Total workload/ 30 hr
3,9
ECTS Credit of the Course
4
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CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
