1	Course Title:	ENZYMOLOGY
2	Course Code:	TIP2072
3	Type of Course:	Optional
4	Level of Course:	First Cycle
5	Year of Study:	2
6	Semester:	4
7	ECTS Credits Allocated:	2
8	Theoretical (hour/week):	1
9	Practice (hour/week) :	0
10	Laboratory (hour/week) :	0
11	Prerequisites:	None
12	Recommended optional programme components:	None
13	Language:	Turkish
14	Mode of Delivery:	Face to face
15	Course Coordinator:	Öğr.Gör. Tıp Fakültesi Öğrenci İşleri
16	Course Lecturers:	Prof. Dr. Esma GÜR
17	Contactinformation of the Course Coordinator:	esma@uludag.edu.tr (224) 2953911 U.Ü. Tıp Fakültesi, Tıbbi Biyokimya AD, Görükle- BURSA
18	Website:	http://tip.uludag.edu.tr/egitim11/secmeli-ders-rehberi.doc
19	Objective of the Course:	Enzymes have vital roles in healthy development and function of living organisms. Moreover, enzymes are valuable parameters for diagnosis and treatment of many clinical situations. It is very important to understand the structure, mechanism of action and the principles in enzyme action to evaluate the enzymatic reactions in the organism. The aim of this course is to explain the enzyme structure, priciples of enzymatic reactions, isoenzymes and their importance as well as enzyme inhibition and to review methods in enzyme activity measurement.
20	Contribution of the Course to Professional Development

21

Learning Outcomes:

1 To explain the enzyme structure and enzyme action; 2 To define the roles of cofactors in enzymatic reactions; 3 To explain the importance of enzymes that have special value in clinical diagnosis and follow up;

22	Course Content:

Week	Theoretical	Practical
1	Enzyme structure and features
2	The princliples of enzymatic catalysis
3	Cofactors
4	Cofactors
5	Enzyme inhibition-I
6	Enzyme inhibition-II
7	Regulation of enzyme activity
8	Isoenzymes-I
9	Isoenzymes-II
10	Isoenzymes in clinical practice-I
11	Isoenzymes in clinical practice-II
12	Enzymes in diagnosis-I
13	Enzymes in diagnosis-II
14	Methods in measuring enzyme activity

23	Textbooks, References and/or Other Materials:	1.Harper’s Illustrated Biochemistry.Murray, Grammer, Mayes, Rodwell. Appleton &Lange, 28e. 2.Tietz textbook of Clinical Chemistry. Ashwood. Saunders (1994). 3.Color Atlas of Biochemistry. Koolman, Röhm. Thieme. (1996).
24	Assesment

TERM LEARNING ACTIVITIES	NUMBER	PERCENT
Midterm Exam	1	40
Quiz	0	0
Homeworks, Performances	0	0
Final Exam	1	60
Total	2	100
Contribution of Term (Year) Learning Activities to Success Grade		40
Contribution of Final Exam to Success Grade		60
Total		100
Measurement and Evaluation Techniques Used in the Course
Information

25

ECTS / WORK LOAD TABLE

Activites	NUMBER	TIME [Hour]	Total WorkLoad [Hour]
Theoretical	14	1	14
Practicals/Labs	0	0	0
Self Study and Preparation	14	1,5	21
Homeworks, Performances	0	0	0
Projects	0	0	0
Field Studies	0	0	0
Midtermexams	1	14	14
Others	0	0	0
Final Exams	1	6	6
Total WorkLoad			55
Total workload/ 30 hr			1,83
ECTS Credit of the Course			2

26	CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
PQ1 PQ2 PQ3 PQ4 PQ5 PQ6 PQ7 PQ8 PQ9 PQ10 PQ11 PQ12 PQ13 PQ14 PQ15 PQ16 LO1 5 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LO2 5 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LO3 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0

LO: Learning Objectives

PQ: Program Qualifications

Contribution Level:

1 Very Low

2 Low

3 Medium

4 High

5 Very High