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Course Title: |
ORGANIC CHEMISTRY LABORATORY |
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Course Code: |
KIM2151 |
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Type of Course: |
Compulsory |
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Level of Course: |
First Cycle |
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Year of Study: |
2 |
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Semester: |
3 |
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ECTS Credits Allocated: |
2 |
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Theoretical (hour/week): |
0 |
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Practice (hour/week) : |
0 |
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Laboratory (hour/week) : |
2 |
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Prerequisites: |
None |
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Recommended optional programme components: |
None |
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Language: |
Turkish |
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Mode of Delivery: |
Face to face |
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Course Coordinator: |
Doç. Dr. SERKAN ÖZTÜRK |
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Course Lecturers: |
- |
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Contactinformation of the Course Coordinator: |
Doç. Dr. Serkan ÖZTÜRK
serkanozturk@uludag.edu.tr
(224)-2955093
Bursa Uludağ Üniversitesi
Fen-Edebiyat Fakültesi
Kimya Bölümü |
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Website: |
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Objective of the Course: |
The aim of the course is to provide students with the necessary laboratory skills related to organic synthesis, isolation and characterization methods. |
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Contribution of the Course to Professional Development |
To learn the main isolation techniques used in the laboratory, to gain the ability to make organic synthesis and organic chemistry laboratory culture |
| Week |
Theoretical |
Practical |
| 1 |
|
Introduction, General information, Safety rules |
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Crystallization: Crystallization of salicylic acid from salicylic acid - sand mixture |
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Distillation: Separation of miscible ethyl acetate and 1-butanol liquids by simple and fractionated distillation techniques |
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Chemically active extraction: Separation of a solid mixture of 3-nitroaniline and benzoic acid by chemically active extraction based on acid-base reactions. (I. Quiz) |
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Isolation of caffeine from tea: Isolation of caffeine from tea solution by extraction method |
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Thin layer chromatography: Definition and types of chromatography, separation of two substances by thin layer chromatography and calculation of Rf values |
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Problem solving, Midterm |
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Reduction of camphor: Reduction of camphor compound to isoborneol compound with NaBH4 |
| 9 |
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Fischer esterification reaction: Esters and their properties, Various preparation methods of esters, Preparation of acetate esters of acetic acid with various alcohols catalyzed by H2SO4 |
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Diels-Alder reaction: Introduction of dienes and dienophiles, mechanism of the Diels-Alder reaction, realization of the Diels-Alder reaction between maleic anhydride and 3-sulfolene. (II. Quiz) |
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Synthesis of adipic acid from cyclohexanone: Oxidation reactions in organic chemistry, Oxidation of cyclohexanone to adipic acid with KMnO4 |
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Sulfolation of tolüene: Electrophilic aromatic substitution reactions, synthesis of sodium p-toluenesulfonate by sulfolating toluene with sulfuric acid |
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Butyl bromide synthesis: Nucleophilic substitution reactions in organic chemistry, synthesis of n-butyl bromide from n-butatol with NaBr and H2SO4 |
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Problem solving, (III. Quiz) |
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Textbooks, References and/or Other Materials: |
1) G. Solomons ve C. Fryhle ;(Çev. Ed. G. Okay ve Y. Yıldırır), Organik Kimya; Literatür Yayınları, 2002.
2) Kenneth L. Williamson ; Macroscale and Microscale Organic Experiments,; D.C. Healt and Company, 1989.
3) Brian S. Furniss, Antony J. Hannaford, Peter W.G. Smith, Austin R. Tatchell; Vogel’s Textbook of Practical Organic Chemistry,; Longman Scientific &Technical,; 1989.
4) Ender Erdik, Metin Obalı, Nadire Yüksekışık, Atilla Öktemer, Tarık Pekel, İhsanoğlu; Denel Organic Kimya; A.Ü.F.F Döner Sermaye İşletmesi yayınları, 2000.
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Assesment |
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