COURSE SYLLABUS

GENERAL PHARMACOLOGY

1	Course Title:	GENERAL PHARMACOLOGY
2	Course Code:	TFR5001
3	Type of Course:	Compulsory
4	Level of Course:	Second Cycle
5	Year of Study:	1
6	Semester:	1
7	ECTS Credits Allocated:	2
8	Theoretical (hour/week):	1
9	Practice (hour/week) :	0
10	Laboratory (hour/week) :	0
11	Prerequisites:	None
12	Recommended optional programme components:	None
13	Language:	Turkish
14	Mode of Delivery:	Face to face
15	Course Coordinator:	Prof. Dr. R.Levent BÜYÜKUYSAL
16	Course Lecturers:	Yok
17	Contactinformation of the Course Coordinator:	lrbuyuk@uludag.edu.tr 4428830 UÜ Tıp Fak. Tıbbi Farmakoloji Anabilim Dalı
18	Website:
19	Objective of the Course:	To learn about the basic principles of pharmacokinetics and pharmacodynamics of drugs.
20	Contribution of the Course to Professional Development	Be able to comment on the changes of drug effect that may occur depending on the their pharmacocinetic and pharmacodynamic properties.

Learning Outcomes:

1	Knowing the pharmacokintetics properties of drugs .;
2	Knowlede about the mechanism of drug action.;
3	Be able to comment on the receptor and postreceptor events.;
4	Be able to comment on the changes of drug effect that may occur depending on the their pharmacokinetic properties.;
5	Be able to comment on the changes of drug effect that may occur depending on the their pharmacodynamic properties.;
6	Interpretation of the plasma concentration-time curves of drugs;
7	Kowing the dose-effects relationship of drugs and interpret the graphs showing this relationship.;
8	In the case of drug action is different than expected, make a comment about the factors that caused it.;
9	Able to perform basic pharmacokinetic calculations.;

22	Course Content:

Week	Theoretical	Practical
1	Definitaions and introduction to pharmacokinetic: Drug absorbtion.
2	Routes of drug administration and pharmacokinetic properties associated in these routes.
3	Distribition of drugs.
4	Metabolism of drugs.
5	Elimination of drugs.
6	Receptor concept and mechanism of drug effect.
7	Plasma consentration-time curves of drugs.
8	Relationship between the dose and drug effect.
9	Pharmacokinetic drug interactions.
10	Pharmacodynamic drug interactions.
11	Factors that alter the drug effect.
12	Advers drug effects.
13	Clinical drug research.
14	Basic pharmacokinetic calculatoins.

23	Textbooks, References and/or Other Materials:	Rasyonel Tedavi Yönünden Tıbbi Farmakoloji, Oğuz Kayaalp, 12. Baskı, Pelikan Yayınevi, 2009, ISBN 978-9944-119-74-0 Goodman and Gilman’s The Pharmacological Basis of Therapeutics, Edit. JG Hardman, LE Limbird, Tenth Edition, McGrav Hill, 2001, ISBN 0-07-135469-7 Basic and Clinical Pharmacology, Edit. BG Katzung, SB Masters, AJ Trevor, 11th Edition, 2009, ISBN 978-007-127118-9
24	Assesment

TERM LEARNING ACTIVITIES	NUMBER	PERCENT
Midterm Exam	0	0
Quiz	0	0
Homeworks, Performances	0	0
Final Exam	1	100
Total	1	100
Contribution of Term (Year) Learning Activities to Success Grade		0
Contribution of Final Exam to Success Grade		100
Total		100
Measurement and Evaluation Techniques Used in the Course	Final exam
Information	Clasical examination.

ECTS / WORK LOAD TABLE

CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS

LO: Learning Objectives

PQ: Program Qualifications

Contribution Level:

1 Very Low

2 Low

3 Medium

4 High

5 Very High