COURSE SYLLABUS

NUCLEIC ACIDS METABOLISM

1	Course Title:	NUCLEIC ACIDS METABOLISM
2	Course Code:	BIO5408
3	Type of Course:	Optional
4	Level of Course:	Second Cycle
5	Year of Study:	1
6	Semester:	2
7	ECTS Credits Allocated:	6
8	Theoretical (hour/week):	3
9	Practice (hour/week) :	0
10	Laboratory (hour/week) :	0
11	Prerequisites:	None
12	Recommended optional programme components:	None
13	Language:	Turkish
14	Mode of Delivery:	Face to face
15	Course Coordinator:	Doç. Dr. EGEMEN DERE
16	Course Lecturers:	Prof. Dr. Ferda ARI
17	Contactinformation of the Course Coordinator:	Doç. Dr. Egemen DERE Bursa Uludağ Üniversitesi Fen Ed. Fak Biyoloji Bl. Moleküler Biyoloji Anabilim Dalı Tel: 0 224 41792 edere@uludag.edu.tr
18	Website:
19	Objective of the Course:	The aim of the course is to comprehend the structure of DNA and RNA, the synthesis and destruction of nucleic acids. It is to provide understanding the metabolic importance of nucleic acids to students. Thus, we are targeted to be more successful the problems with regard to nucleic acids faced by the student's graduate studies.
20	Contribution of the Course to Professional Development	DNA and RNA form the basis of the vital functions of the cell. Understanding the structure and function of nucleic acids and how they are affected by internal and external factors will enable students to better comment on their research topics.

Learning Outcomes:

1	Students can grasp the molecular structures and organizations of nucleic acid;
2	Students can compare different models of DNA and RNA in life;
3	Students can understand purin and pyrimidine synthesis;
4	Students can compare replication models in prokaryotic and eukaryotic organisms;
5	Students can understand DNA mutation;
6	Students can understand repair mechanism;
7	Students can grasp the functions of Chloroplast and Mitochondrial DNA;
8	Students can understand metabolism disorders of nucleic acids;

22	Course Content:

Week	Theoretical	Practical
1	Structure of nucleic acids modify bases
2	Nucleoside and nucleotide, Digestion of nucleotide
3	Purine biosynthesis and regulation of synthesis
4	Purine catabolism
5	Pyrimidine biosynthesis and regulation of synthesis
6	Pyrimidine catabolism
7	Exam and answer of examination questions, general discussion
8	Polynucleotide -DNA and RNA-
9	Analysis of nucleic acids
10	DNA replication
11	Mutations
12	Repair mechanisms
13	Chloroplast and Mitochondrial DNA
14	Purine and pyrimidine metabolism disorders

23	Textbooks, References and/or Other Materials:	Molecular Biology of the Cell, Alberts –Bray Nucleic Acids, Victor A. Bloomfield
24	Assesment

TERM LEARNING ACTIVITIES	NUMBER	PERCENT
Midterm Exam	1	25
Quiz	0	0
Homeworks, Performances	1	15
Final Exam	1	60
Total	3	100
Contribution of Term (Year) Learning Activities to Success Grade		40
Contribution of Final Exam to Success Grade		60
Total		100
Measurement and Evaluation Techniques Used in the Course	Homework, oral and classical exam
Information	The presentation of the subjects by the students helps the student to understand the lessons better

ECTS / WORK LOAD TABLE

CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS

LO: Learning Objectives

PQ: Program Qualifications

Contribution Level:

1 Very Low

2 Low

3 Medium

4 High

5 Very High