The aim of this course is to have knowledge about nucleotides and metabolic pathways affected by nucleotides, diseases related to nucleotides.
20
Contribution of the Course to Professional Development
Understanding the metabolism of nucleic acids and interpreting related metabolic diseases
21
Learning Outcomes:
1
To be able to define the building blocks of nucleic acids;
2
To be able to explain the nucleotide synthesis mechanisms
;
3
To be able to draw nucleotide degradation pathways
;
4
To be able to analyze nucleotide metabolism disorders
;
5
To be able to interpret the current literature on the subject
;
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Course Content:
Week
Theoretical
Practical
1
Nucleoside-Nucleotide structure,
2
Structure of Nucleic Acids
3
Digestion of nucleic acids
4
Purine biosynthesis
5
Regulation of purine biosynthesis
6
Purine catabolism
7
Pyrimidine biosynthesis
8
Regulation of pyrimidine biosynthesis
9
Pyrimidine catabolism
10
Polynucleotides (DNA-RNA)
11
Synthesis of deoxyribonucleotides
12
Inhibition of the synthesis of Purine and Pyrimidine nucleotides
13
Nucleotide metabolism disorders
14
Current studies in the literature
23
Textbooks, References and/or Other Materials:
Donald Voeth, Judith G Voet. Biochemistry. Fourth edition,2010. David L Nelson, Michael M Cox. Lehninger Principles of Biochemistry. Fifth edition, 2008. Robert Murray, David Bender, Kathleen M. Botham, Peter J. Kennelly, Victor Rodwell, P. Anthony Weil. Harpers Illustrated Biochemistry 29th Edition, 2012. Lippincott's Illustrated Reviews: Biochemistry. Pamela C. Champe Richard A. Harvey 2011. Marks Basic Medical Biochemistry; a clinical approach, Michael Lieberman,Allan D. Marks 2009
24
Assesment
TERM LEARNING ACTIVITIES
NUMBER
PERCENT
Midterm Exam
0
0
Quiz
0
0
Homeworks, Performances
0
0
Final Exam
1
100
Total
1
100
Contribution of Term (Year) Learning Activities to Success Grade
0
Contribution of Final Exam to Success Grade
100
Total
100
Measurement and Evaluation Techniques Used in the Course
Measurement and evaluation are performed according to the Rules & Regulations of Bursa Uludağ University on Undergraduate Education.
Information
25
ECTS / WORK LOAD TABLE
Activites
NUMBER
TIME [Hour]
Total WorkLoad [Hour]
Theoretical
14
3
42
Practicals/Labs
0
0
0
Self Study and Preparation
14
5
70
Homeworks, Performances
0
0
0
Projects
0
0
0
Field Studies
0
0
0
Midtermexams
0
0
0
Others
0
0
0
Final Exams
1
40
40
Total WorkLoad
152
Total workload/ 30 hr
5,07
ECTS Credit of the Course
5
26
CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
