METABOLISM OF CARBOHYDRATES: MAJOR AND MINOR METABOLIC PATHWAYS
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Course Title:
METABOLISM OF CARBOHYDRATES: MAJOR AND MINOR METABOLIC PATHWAYS
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Course Code:
TBK6004
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Type of Course:
Compulsory
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Level of Course:
Third Cycle
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Year of Study:
1
6
Semester:
2
7
ECTS Credits Allocated:
8
8
Theoretical (hour/week):
2
9
Practice (hour/week) :
2
10
Laboratory (hour/week) :
0
11
Prerequisites:
No
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Recommended optional programme components:
None
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Language:
Turkish
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Mode of Delivery:
Face to face
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Course Coordinator:
Prof. Dr. MELEHAT DİRİCAN
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Course Lecturers:
Prof.Dr. Melahat DİRİCAN
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Contactinformation of the Course Coordinator:
mdirican@uludag.edu.tr 2953912 Uludağ Üniversitesi, Tıp Fakültesi Biyokimya Anabilim Dalı 16059, Bursa
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Website:
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Objective of the Course:
The aim of this course is to teach the structural and functional features of carbohydrates in human body in an advanced level.
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Contribution of the Course to Professional Development
Basic metabolic pathways of carbohydrates are learned.
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Learning Outcomes:
1
To identify the major classes of carbohydrates and give examples of each;
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To explain the fate of glucose and other carbohydrates in the body including yhe pathways of glycolysis, glycogenesis and the hexose monophosphate shunt;
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To explain the importance of gluconeogenesis and glycogenolysis for maintaining blood sugar concentrations;
4
To relate the mechanism for glucose and other carbohydrates to act as reducing substance;
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Course Content:
Week
Theoretical
Practical
1
Structures of carbohydrates
Qualitative methods for total reducing substance in urine (Fehling)
2
Digestion and absorbtion of carbohydrates
Polarimetry
3
Glycolysis
Osazone testing
4
Regulation of glycolysis
Identification of sugars
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Oxidation of pyruvate
Glucose measurements in whole blood
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TCA cycle
Glucose oxidase method
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Regulation of TCA cycle
Measurements of lactate
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Structure of glycogen and glycogen synthesis
Measurements of pyruvate
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Glycogenolysis
Postprandial glucose measurements
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Gluconeogenesis and regulation of gluconeogenesis
OGTT and interpretation
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Pentose phosphate pathway
Bial’s test
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Uronic acid pathway
Selivanoff’s test
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Glycosaminoglycans
Mucic acid test
14
Mucopolysaccharidoses and glycogen storage diseases
Tollen’s test
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Textbooks, References and/or Other Materials:
1- Tietz textbook of clinical chemistry, Eds: Burtis Carl, Ashwood Edward, Saunders Company, 1994 2- Biyokimya Eds: Gürdöl Figen, Ademoğlu Evin, Nobel Tıp Kitabevleri, 2006 3- Harper's Illustrated Biochemistry, 27th Edition, Eds: Robert K. Murray, Daryl K. Granner, Victor W. Rodwell, The McGraw-Hill Companies, Inc. 2006
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Assesment
TERM LEARNING ACTIVITIES
NUMBER
PERCENT
Midterm Exam
0
0
Quiz
0
0
Homeworks, Performances
0
0
Final Exam
1
100
Total
1
100
Contribution of Term (Year) Learning Activities to Success Grade
0
Contribution of Final Exam to Success Grade
100
Total
100
Measurement and Evaluation Techniques Used in the Course
There is a multiple-choice test/assay final exam.
Information
One final exam is scheduled.
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ECTS / WORK LOAD TABLE
Activites
NUMBER
TIME [Hour]
Total WorkLoad [Hour]
Theoretical
14
2
28
Practicals/Labs
14
2
28
Self Study and Preparation
14
10
140
Homeworks, Performances
0
10
20
Projects
0
0
0
Field Studies
0
0
0
Midtermexams
0
0
0
Others
0
0
0
Final Exams
1
20
20
Total WorkLoad
236
Total workload/ 30 hr
7,87
ECTS Credit of the Course
8
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CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
