1	Course Title:	SECONDER METABOLITES
2	Course Code:	KIM5060
3	Type of Course:	Optional
4	Level of Course:	Third Cycle
5	Year of Study:	1
6	Semester:	2
7	ECTS Credits Allocated:	6
8	Theoretical (hour/week):	3
9	Practice (hour/week) :	0
10	Laboratory (hour/week) :	0
11	Prerequisites:	-
12	Recommended optional programme components:	None
13	Language:	Turkish
14	Mode of Delivery:	Face to face
15	Course Coordinator:	Doç. Dr. ASLI GÖÇENOĞLU SARIKAYA
16	Course Lecturers:	-
17	Contactinformation of the Course Coordinator:	Doç. Dr. Aslı GÖÇENOĞLU SARIKAYA agocenoglu@uludag.edu.tr Bursa Uludağ Üniversitesi Fen Edebiyat Fakültesi Kimya Bölümü, Görükle-Bursa, 16059
18	Website:
19	Objective of the Course:	The aim of the course is to give students a comprehensive background on important microbial secondary products and their production, along with their advantages and disadvantages.
20	Contribution of the Course to Professional Development	To learn important microbial secondary products and their production.

21

Learning Outcomes:

1 Knows the difference between primary and secondary metabolites; 2 Have knowledge about secondary metabolite production processes;

22	Course Content:

Week	Theoretical	Practical
1	Secondary metabolite concept
2	Primary metabolism
3	Secondary metabolism
4	Basic reactions that take place in secondary metabolism
5	Antibiotics and other biologically active microbial metabolites
6	Biology of secondary metabolite producing microorganisms
7	Investigation of new secondary metabolites from microorganisms
8	Synthesis of secondary metabolites
9	Strain development and process development
10	Biological transformations
11	Synthesis and regulation of antibiotics
12	Pigment production
13	Production of polypronaoids and alkaloids
14	Production of polyketides and tepenoids

23	Textbooks, References and/or Other Materials:	Biotechnology Secondary Metabolites: Plants and Microbes (Second Edition) edited by K.G. Ramawat and J.M. Merillon Science Publishers, 2007. Biotechnology of Antibiotics and other Bioactive Microbial Metabolites by G. Lancini, R. Lorenzetti, Springer; 1st Edition, 1993
24	Assesment

TERM LEARNING ACTIVITIES	NUMBER	PERCENT
Midterm Exam	1	40
Quiz	0	0
Homeworks, Performances	0	0
Final Exam	1	60
Total	2	100
Contribution of Term (Year) Learning Activities to Success Grade		40
Contribution of Final Exam to Success Grade		60
Total		100
Measurement and Evaluation Techniques Used in the Course	Writing exam
Information	Writing exam

25

ECTS / WORK LOAD TABLE

Activites	NUMBER	TIME [Hour]	Total WorkLoad [Hour]
Theoretical	14	3	42
Practicals/Labs	0	0	0
Self Study and Preparation	14	6	84
Homeworks, Performances	0	0	0
Projects	0	0	0
Field Studies	0	0	0
Midtermexams	1	20	20
Others	0	0	0
Final Exams	1	30	30
Total WorkLoad			176
Total workload/ 30 hr			5,87
ECTS Credit of the Course			6

26	CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
PQ1 PQ2 PQ3 PQ4 PQ5 PQ6 PQ7 PQ8 PQ9 PQ10 LO1 4 4 5 5 5 5 5 4 5 4 LO2 4 4 5 5 5 5 5 4 5 4

LO: Learning Objectives

PQ: Program Qualifications

Contribution Level:

1 Very Low

2 Low

3 Medium

4 High

5 Very High