| 1 | Course Title: | GAMETOGENESIS, FERTILIZATION AND IMPLANTATION |
| 2 | Course Code: | VDT6001 |
| 3 | Type of Course: | Compulsory |
| 4 | Level of Course: | Third Cycle |
| 5 | Year of Study: | 1 |
| 6 | Semester: | 1 |
| 7 | ECTS Credits Allocated: | 5 |
| 8 | Theoretical (hour/week): | 2 |
| 9 | Practice (hour/week) : | 2 |
| 10 | Laboratory (hour/week) : | 0 |
| 11 | Prerequisites: | None |
| 12 | Recommended optional programme components: | None |
| 13 | Language: | Turkish |
| 14 | Mode of Delivery: | Face to face |
| 15 | Course Coordinator: | Doç. Dr. BURCU ÜSTÜNER |
| 16 | Course Lecturers: | yok |
| 17 | Contactinformation of the Course Coordinator: |
Doç.Dr.Burcu ÜSTÜNER bbaspinar@uludag.edu.tr, 0224-2941245 Uludağ Üniversitesi Veteriner Fakültesi Dölerme ve Suni Tohumlama AD |
| 18 | Website: | http://saglikbilimleri.uludag.edu.tr/anabilimdallari.php |
| 19 | Objective of the Course: | The aim of the course is to have knowledge about gamete formation, physiology of fertilization and zygote and embryonic development processes. |
| 20 | Contribution of the Course to Professional Development | The outcome of the course is to determine the age of use in breeding on the basis of species for economic profitability in animal husbandry and to use gamete physiology to determine the insemination time to obtain the highest pregnancy rates. |
| 21 | Learning Outcomes: |
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| 22 | Course Content: |
| Week | Theoretical | Practical |
| 1 | Determining the age of puberty and use in breeding in male and female animals | Routine sperm examinations in the andrology laboratory |
| 2 | Evaluation of ogenesis on the basis of species and ovulation | Oocyte recovery in ovarian material brought from slaughterhouse |
| 3 | Spermatogenesis and factors affecting spermatogenesis | Semen preparation for in vitro fertilization (IVF). |
| 4 | Ultrastructural structure of semen and tests used to determine fertility in male animals | Routine microscopic tests used to determine the fertility of semen |
| 5 | Transport of sperm in male and female genital canal | Determination of plasma membrane integrity of spermatozoon by advanced sperm analysis techniquess |
| 6 | Fertilization process and formation of female and male pronucleus | Evaluation and importance of sperm DNA integrity |
| 7 | Embryonic development and maternal recognition | Induction of capacitation in semen and acrosomal examination |
| 8 | In vitro fertilization protocols used in animals | Preparation of IVF (in vitro fertilization) stock mediums |
| 9 | Assisted Reproductive Technologies (ART) used in animals | Preparation of daily IVF mediums |
| 10 | Cryopreservation of semen and its using for artificial insemination | Preparation of extenders which used in sperm cryopreservation |
| 11 | Lyophilisation of semen | Evaluation of lyophilized semen |
| 12 | Sexed semen technology | Interpretation of oxidative stress parameters in semen |
| 13 | Determination of gender in embryo before transfer | Loading the embryo in straw, vitrification protocols and preparation of vitrification solutions |
| 14 | Superovulation and embryo transfer in farm animals | Determining the quality of embryo to be transferred |
| 23 | Textbooks, References and/or Other Materials: |
NOAKES, D.E., PARKINSON, T.J., ENGLAND, G.C.W., Arthur’s Veterinary Reproduction and Obstetrics, Saunders Inc., New York, USA GORDON, I., Laboratory Production of Cattle Embryos, 2nd edition. CABI Publisihg, Cambridge,MA, USA, 2003. GARDNER, D.K., WEISSMAN, A., HOWLES, C.M., SHOHAM Z.,Textbook of Assisted Reproductive Techniques. Laboratory ant Clinical Perspectives. 2nd edition. Taylor & Francis, London, UK, 2004. HAFEZ, E.S.E., HAFEZ, B., Reproduction in farm animals. Lippincott Williams&Wilkins, 2000. LINDSAY, D., Breeding the flock, Inkata press, 1998. |
| 24 | Assesment |
| TERM LEARNING ACTIVITIES | NUMBER | PERCENT |
| Midterm Exam | 0 | 0 |
| Quiz | 0 | 0 |
| Homeworks, Performances | 0 | 0 |
| Final Exam | 1 | 100 |
| Total | 1 | 100 |
| Contribution of Term (Year) Learning Activities to Success Grade | 0 | |
| Contribution of Final Exam to Success Grade | 100 | |
| Total | 100 | |
| Measurement and Evaluation Techniques Used in the Course | Exams that including classical questions | |
| Information | Successfull, unsuccessful | |
| 25 | ECTS / WORK LOAD TABLE |
| Activites | NUMBER | TIME [Hour] | Total WorkLoad [Hour] |
| Theoretical | 14 | 1 | 14 |
| Practicals/Labs | 14 | 2 | 28 |
| Self Study and Preparation | 10 | 5 | 50 |
| Homeworks, Performances | 0 | 5 | 10 |
| Projects | 1 | 6 | 6 |
| Field Studies | 0 | 0 | 0 |
| Midtermexams | 0 | 0 | 0 |
| Others | 0 | 0 | 0 |
| Final Exams | 1 | 42 | 42 |
| Total WorkLoad | 150 | ||
| Total workload/ 30 hr | 5 | ||
| ECTS Credit of the Course | 5 |
| 26 | CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| LO: Learning Objectives | PQ: Program Qualifications |
| Contribution Level: | 1 Very Low | 2 Low | 3 Medium | 4 High | 5 Very High |