COURSE SYLLABUS

THE OXIDATIVE PHOSPHORYLATION AND MITOCHONDRIAL TRANSPORT SYSTEMS

1	Course Title:	THE OXIDATIVE PHOSPHORYLATION AND MITOCHONDRIAL TRANSPORT SYSTEMS
2	Course Code:	VBK6020
3	Type of Course:	Optional
4	Level of Course:	Third Cycle
5	Year of Study:	1
6	Semester:	2
7	ECTS Credits Allocated:	2
8	Theoretical (hour/week):	1
9	Practice (hour/week) :	0
10	Laboratory (hour/week) :	0
11	Prerequisites:	Yok
12	Recommended optional programme components:	None
13	Language:	Turkish
14	Mode of Delivery:	Face to face
15	Course Coordinator:	Prof. Dr. MELTEM TANRIVERDİ
16	Course Lecturers:	-
17	Contactinformation of the Course Coordinator:	melcetin@uludag.edu.tr 0532 4875175 U.Ü.Veteriner Fakültesi Biyokimya ABD
18	Website:
19	Objective of the Course:	To be able to comprehend the use of products obtained in metabolic events in living organisms in energy generation
20	Contribution of the Course to Professional Development	To establish a link between oxidative phosphorylation and metabolic events, Identify the disorders related to oxidative phosphorylation, To be able to transfer the knowledge gained on oxidative phosphorylation

Learning Outcomes:

1	To be able to describe the properties of mitochondria where oxidative phosphorylation takes place;
2	To be able to explain the enzyme systems and elements involved in oxidative phosphorylation;
3	Understanding the factors that prevent oxidative phosphorylation;
4	To be able to discuss the theories about oxidative phosphorylation;
5	To establish a link between oxidative phosphorylation and metabolic events;
6	To be able to obtain new information about oxidative phosphorylation;
7	Identify the disorders related to oxidative phosphorylation;
8	To be able to transfer the knowledge gained on oxidative phosphorylation;

22	Course Content:

Week	Theoretical	Practical
1	The properties of mitochondrial membrane
2	Mitochondrial transport mechanisms
3	Oxidative phosphorylation
4	The components of the electron transport chain
5	NADH-Q reductase complex and coenzyme Q
6	Cytochromes
7	Coupling of electrone transport and ATP synthesis
8	Uncoupling agents
9	ATP synthesis hypotheses
10	Chemiosmotic teori
11	ATP gain in glycolysis and TCA cycle
12	ATP gain in oxidation of fatty acids
13	General overview of topics
14	Discussion

23	Textbooks, References and/or Other Materials:	Lehninger Principles of Biochemistry David L. Nelson, Michael M. Cox, 2005. Principles of Biochemistry, H. R. Horton, L. A. Moran, R. S. Ochs, J. D. Rawn, K. G. Scrimgeour, 2002. Biochemistry (5th edition) Berg JM., 2002. Metabolism at a Glance (At a Glance) D. K. Granner,J. G. Salway, 2004. Biyokimya, L. Kalaycıoğlu, B. Serpek, M. Nizamlıoğlu, N. Başpınar, A. M. Tiftik, 2000.
24	Assesment

TERM LEARNING ACTIVITIES	NUMBER	PERCENT
Midterm Exam	0	0
Quiz	0	0
Homeworks, Performances	0	0
Final Exam	1	100
Total	1	100
Contribution of Term (Year) Learning Activities to Success Grade		0
Contribution of Final Exam to Success Grade		100
Total		100
Measurement and Evaluation Techniques Used in the Course	Final exam
Information

ECTS / WORK LOAD TABLE

CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS

LO: Learning Objectives

PQ: Program Qualifications

Contribution Level:

1 Very Low

2 Low

3 Medium

4 High

5 Very High