COURSE SYLLABUS

ADVANCED ORGANIC CHEMISTRY

1	Course Title:	ADVANCED ORGANIC CHEMISTRY
2	Course Code:	KIM5004
3	Type of Course:	Compulsory
4	Level of Course:	Second Cycle
5	Year of Study:	1
6	Semester:	2
7	ECTS Credits Allocated:	6
8	Theoretical (hour/week):	3
9	Practice (hour/week) :	0
10	Laboratory (hour/week) :	0
11	Prerequisites:	None
12	Recommended optional programme components:
13	Language:	Turkish
14	Mode of Delivery:	Face to face
15	Course Coordinator:	Doç.Dr. NEVİN ARIKAN ÖLMEZ
16	Course Lecturers:	Prof. Dr. Necdet COŞKUN Prof. Dr. Mustafa TAVASLI
17	Contactinformation of the Course Coordinator:	narikan@uludag.edu.tr +90 224 29 41 731 Uludağ Üniversitesi, Fen-Edebiyat Fakültesi, Kimya Bölümü, 16059 Görükle / BURSA,
18	Website:
19	Objective of the Course:	The aim of the course is, to examine the organic chemistry topics in more detail which were seen by student's during the undergraduate education . Fully comprehend these issues, if have completation of the missing issues, and to provide a background for easily use their knowledges in organic chemistry in their fields
20	Contribution of the Course to Professional Development	To learn the graduate-level organic chemistry knowledge

Learning Outcomes:

1	Having detailed information about the chemical bondings in organic molecules;
2	Having adequate knowledge about the three-dimensional structure and stereochemical properties of organic molecules ;
3	Recognition of reactive intermediates observed in reactions and writing reactions related to their formation;
4	Developing the ability to propose a valid mechanism for reactions;
5	Recognition the acid-base character agents. To explain the effect of structure on reactivity.;

22	Course Content:

Week	Theoretical	Practical
1	Localized chemical bonding Atomic orbitals, the types of chemical bonds and the formation of organic compounds, hybridization, bond lengths and energies Homolytic and heterolytically bond disossiation
2	Delocalized chemical bonding Molecules containing delocalized bonding Resonance and resonance rules Aromaticity, hiperconjugation
3	Stereochemistry Optical activity and chirality Fischer projection formulas The absolute configuration, resolution methods
4	Stereochemistry Optical purity, cis-trans isomerization, in the open-chain and ring structures, E, Z isomerization Conformational analysis, open-chain and ring structures
5	Stereochemistry Newman projection, the strained ring systems Conformation determination methods X-ray, NMR
6	Reactive intermediate products Carbocations, the structure and stability Benzylic, allylic structures Nonclassical carbocations the formation of carbocation
7	Reactive intermediate products Carbanions, the structure and stability Organometallic compounds Formation reactions of carbanions
8	Reactive intermediate products Free radicals, the structure and stability Radical formation reactions Radical ions Carbenes and Nitrenes structure and stability, their formation
9	Mechanisms of organic reactions Definition of mechanism Mechanism types of species, and the reaction Thermodynamic and kinetic requirements Hammond postulate
10	Mechanisms of organic reactions Mechanism determination methods Characterization of products and detection of intermediate products Catalytic studies
11	Mechanisms of organic reactions Isotope labeling Stereochemical evidence Kinetic evidences and isotope effect
12	Acids and bases Definitions of acid-base in organic chemistry Basic and acid solvents Acid-base catalysts The effect of the structure and the environment over the acidity or alkalinity
13	The effect of structure on reactivity Inductive effects, resonance and field effects Steric effects, the effects of Conformation
14	The effect of structure on reactivity Quantitative measurements concerning the effect of structure on reactivity

23	Textbooks, References and/or Other Materials:	1] Jerry March, Advanced Organic Chemistry, Wiley-Interscience, 2001 [2] Reinhard Bruckner, Advanced Organic Chemistry, Academic Press, 2001 [3] Milton Harris, Carl c. Wamser, Fundamentals of Organic Reaction Mechanisms, John-Wiley, 1976 [4] Graham Solomons, Craig Fyrhle, Organic Chemistry, Wiley, 1995
24	Assesment

TERM LEARNING ACTIVITIES	NUMBER	PERCENT
Midterm Exam	1	40
Quiz	0	0
Homeworks, Performances	0	0
Final Exam	1	60
Total	2	100
Contribution of Term (Year) Learning Activities to Success Grade		40
Contribution of Final Exam to Success Grade		60
Total		100
Measurement and Evaluation Techniques Used in the Course	It is evaluated by midterm exam, and final exam, which consists of classical questions, and homework.
Information

ECTS / WORK LOAD TABLE

Activites	NUMBER	TIME [Hour]	Total WorkLoad [Hour]
Theoretical	14	3	42
Practicals/Labs	0	0	0
Self Study and Preparation	14	2	28
Homeworks, Performances	0	0	0
Projects	0	0	0
Field Studies	0	0	0
Midtermexams	1	55	55
Others	0	0	0
Final Exams	1	55	55
Total WorkLoad			180
Total workload/ 30 hr			6
ECTS Credit of the Course			6

CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS

	PQ2	PQ3	PQ4
LO1	5	5	0
LO2	5	5	0
LO3	5	5	5
LO4	0	0	0
LO5	5	5	0

LO: Learning Objectives

PQ: Program Qualifications

Contribution Level:

1 Very Low

2 Low

3 Medium

4 High

5 Very High