1	Course Title:	REGULATION BY ENZYMES
2	Course Code:	BIO6404
3	Type of Course:	Optional
4	Level of Course:	Third Cycle
5	Year of Study:	1
6	Semester:	2
7	ECTS Credits Allocated:	6
8	Theoretical (hour/week):	3
9	Practice (hour/week) :	0
10	Laboratory (hour/week) :	0
11	Prerequisites:	None
12	Recommended optional programme components:	None
13	Language:	Turkish
14	Mode of Delivery:	Face to face
15	Course Coordinator:	Doç. Dr. EGEMEN DERE
16	Course Lecturers:	Prof. Dr. Ferda ARI
17	Contactinformation of the Course Coordinator:	Doç. Dr. Egemen DERE Bursa Uludağ Üniversitesi Fen Ed. Fak Biyoloji Bl. Moleküler Biyoloji Anabilim Dalı Tel: 0 224 41792 edere@uludag.edu.tr
18	Website:
19	Objective of the Course:	The aim of the course is to comprehend structures of enzyme and regulations. To explain the importance of enzymes in metabolism.
20	Contribution of the Course to Professional Development

21

Learning Outcomes:

1 He/she can grasp in relation to Enzyme Substrate; 2 He/she can understand to enzyme inhibitory and inhibitions; 3 He/she can understand to enzyme activators and activations; 4 He/she can grasp the roles of high energy compounds in enzyme regulation; 5 He/she can grasp to structure and function of allosteric enzymes; 6 He/she can understand the importance of enzyme kinetic in enzymatic regulation; 7 He/she can learn to regulation of some metabolic pathways;

22	Course Content:

Week	Theoretical	Practical
1	Enzyme Substrate Complex formation
2	Investigation of enzyme activity center
3	Enzyme inhibitory and inhibitions
4	Enzyme activators and activations
5	The roles of high energy compounds in enzyme regulation
6	Allosteric enzymes
7	Exam and answer of examination questions, general discussion
8	Some important allosteric enzymes
9	Enzyme kinetics
10	Feedback mechanism in enzymatic regulation
11	Regulation of metabolism
12	Control of glycolisis metabolism
13	Control of glycogen metabolism
14	Control of protein metabolism

23	Textbooks, References and/or Other Materials:	Allosteric Regulatory Enzymes, Thomas Traut Enzyme Biocatalysis, Andres Biochemistry, Zubay
24	Assesment

TERM LEARNING ACTIVITIES	NUMBER	PERCENT
Midterm Exam	1	25
Quiz	0	0
Homeworks, Performances	2	15
Final Exam	1	60
Total	4	100
Contribution of Term (Year) Learning Activities to Success Grade		40
Contribution of Final Exam to Success Grade		60
Total		100
Measurement and Evaluation Techniques Used in the Course
Information

25

ECTS / WORK LOAD TABLE

Activites	NUMBER	TIME [Hour]	Total WorkLoad [Hour]
Theoretical	14	3	42
Practicals/Labs	0	0	0
Self Study and Preparation	13	6	78
Homeworks, Performances	2	14	28
Projects	0	0	0
Field Studies	0	0	0
Midtermexams	1	3	3
Others	5	6	30
Final Exams	1	3	3
Total WorkLoad			184
Total workload/ 30 hr			6,13
ECTS Credit of the Course			6

26	CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
PQ1 PQ2 PQ3 PQ4 PQ5 PQ6 PQ7 PQ8 PQ9 PQ10 PQ11 LO1 3 3 4 2 4 3 3 4 3 3 3 LO2 2 3 4 2 4 3 3 3 3 3 2 LO3 2 3 4 2 4 3 3 3 3 3 3 LO4 4 3 4 2 4 3 4 3 4 3 2 LO5 4 4 4 2 4 4 4 4 4 5 3 LO6 5 4 4 2 4 4 4 4 4 5 3 LO7 2 3 4 2 4 3 3 3 3 3 3

LO: Learning Objectives

PQ: Program Qualifications

Contribution Level:

1 Very Low

2 Low

3 Medium

4 High

5 Very High