Türkçe English Rapor to Course Content
COURSE SYLLABUS
BIOCHEMISTRY OF ENDOCRINE SYSTEM
1 Course Title: BIOCHEMISTRY OF ENDOCRINE SYSTEM
2 Course Code: TBK6006
3 Type of Course: Optional
4 Level of Course: Third Cycle
5 Year of Study: 1
6 Semester: 2
7 ECTS Credits Allocated: 5
8 Theoretical (hour/week): 1
9 Practice (hour/week) : 0
10 Laboratory (hour/week) : 0
11 Prerequisites:
12 Recommended optional programme components: None
13 Language: Turkish
14 Mode of Delivery: Face to face
15 Course Coordinator: Prof. Dr. EMRE SARANDÖL
16 Course Lecturers: yok
17 Contactinformation of the Course Coordinator: Prof. Dr. H. Asuman Tokullugil
atokullu@uludag.edu.tr (224) 2953901
U.Ü. Tıp Fakültesi, Tıbbi Biyokimya AD, Görükle- BURSA
18 Website:
19 Objective of the Course: The aim of this course is to teach the structures, biosynthesis, secretion and metabolism of hormones . Following; in order to teach the effects of hormones in the human body , some of the endocrinological tests and their evaluation in the clinics are given as examples.
20 Contribution of the Course to Professional Development Contribution to academic development
21 Learning Outcomes:
1 To explain; The SIGNAL TRANSMISSION SYSTEMS ;
2 To list ; The RECEPTORS: TYPES AND GENERAL CHARACTERISTICS ;
3 To explain the mechanism of SECONDARY MESSENGER SYSTEMS ;
4 To explain the HORMONES :DEFINITION AND IMPORTANCE IN MEDICINE ;
5 To list the CLASSIFICATION OF HORMONES;
6 To explain the MODE OF ACTION OF HORMONES THAT HAVE INTRACELLULER RECEPTORS;
7 To explain the mechanism of NUCLEAR RECEPTORS.;
8 To explain the THYROID HORMONES AND IODINE METABOLISM,connected with nuclear receptors.;
9 To explain the MODE OF ACTION OF HORMONES THAT HAVE INTRACELLULER RECEPTORS;
10 To explain the MODE OF ACTION OF HORMONES THAT HAVE CELL SURFACE RECEPTORS;
22 Course Content:
Week Theoretical Practical
1 SIGNAL TRANSMISSION SYSTEMS-ENTRY
2 RECEPTORS: TYPES AND GENERAL CHARACTERISTICS
3 SECONDARY MESSENGER SYSTEMS: A-ADENYLATE CYCLASE AND cAMP SYSTEM
4 G-PROTEINS AND EXAMPLES
5 SECONDARY MESSENGER SYSTEMS: B-CALCIUM / PHOSPHATIDYLINOSITOL SYSTEM
6 SECONDARY MESSENGER SYSTEMS: C-CYCLIC GUANOSINE MONOPHOSPHATE (cGMP) SYSTEM D-NITRIC OXIDE (NO)
7 HORMONES :DEFINITION AND IMPORTANCE IN MEDICINE: (EX.:DISORDERS OF HORMONE RECEPTORS )
8 CLASSIFICATION OF HORMONES
9 MODE OF ACTION OF HORMONES THAT HAVE INTRACELLULER RECEPTORS A-NUCLEAR RECEPTORS. EX.:SYNTHESIS ,METABOLISM AND EFFECTS OF THYROID HORMONES
10 REVIEW OF THYROID HORMONES AND IODINE METABOLISM
11 MODE OF ACTION OF HORMONES THAT HAVE INTRACELLULER RECEPTORS B-CYTOSOLIC RECEPTORS. EX.:GLUCOCORTICOIDS
12 MODE OF ACTION OF HORMONES THAT HAVE CELL SURFACE RECEPTORS
13 METABOLIC EFFEECTS OF GLUCAGON AND ADRENALINE : EFFECTS ON GLYCOLYSIS , GLUCONEOGENESIS , GLYCOGENOLYSIS AND GLYCOGENESIS
14 ORGANIZATION , LOCALIZATION AND REGULATION OF ENDOCRINE SYSTEM
23 Textbooks, References and/or Other Materials: 1-MURRAY R.K. , GRANNER D.K. , MAYES P.A. , RODWELL V.W. HARPER’S BİYOKİMYA .Bölüm 20,44,46,49,51/(Çev.Editörü: Dikmen N.,Özgüven T.)
25.Baskı,Nobel Tıp,İstanbul,2004. ss:199-208,534-550,561-567,588-602,610-625
2-HARVEY R.A. , CHAMPE P.C. LİPPİNCOTT’S ILLUSTRATED REVIEWS BIOCHEMİSTRY .Bölüm: 11,23.(Çev.Editörü:Ulukaya E.) 3.Baskı , Nobel Tıp ,
2007, İstanbul. ss.123-135,305-319
3-BURTIS C.A. , ASHWOOD E.R. KLİNİK KİMYADA TEMEL İLKELER , TIETZ .Bölüm:26,27,40/ (Çev.Editörü:Aslan D.) 5.Baskı,Palme yayıncılık,Ankara,2005. ss.518-529,529-543,839-857.
4-NELSON D.L. , MICHEAL M.C. LEHNINGER BİOKİMYANIN İLKELERİ.Bölüm: 13,14,23/ (Çev.Editörü:Kılıç N. ) 3.Baskı,Palme yayıncılık, Ankara, 2005.ss:437-485,485-527,869-907.
5-BHAGAVAN N.V./ BHAGAVAN CHEMISTRY . chapter:13 . 2.Edition,Library of C ongress Cataloging in Publication Data,1978.pp:1213-1244.
24 Assesment
TERM LEARNING ACTIVITIES NUMBER PERCENT
Midterm Exam 0 0
Quiz 0 0
Homeworks, Performances 0 0
Final Exam 1 100
Total 1 100
Contribution of Term (Year) Learning Activities to Success Grade 0
Contribution of Final Exam to Success Grade 100
Total 100
Measurement and Evaluation Techniques Used in the Course Measurement and evaluation are performed according to the Rules & Regulations of Bursa Uludağ University on Undergraduate Education.
Information
25 ECTS / WORK LOAD TABLE
Activites NUMBER TIME [Hour] Total WorkLoad [Hour]
Theoretical 14 1 14
Practicals/Labs 0 0 0
Self Study and Preparation 14 9 126
Homeworks, Performances 0 0 0
Projects 0 0 0
Field Studies 0 0 0
Midtermexams 0 0 0
Others 0 0 0
Final Exams 1 10 10
Total WorkLoad 150
Total workload/ 30 hr 5
ECTS Credit of the Course 5
26 CONTRIBUTION OF LEARNING OUTCOMES TO PROGRAMME QUALIFICATIONS
PQ1 PQ2 PQ3 PQ4 PQ5 PQ6 PQ7 PQ8 PQ9 PQ10 PQ11 PQ12
LO1 5 0 0 0 0 0 5 0 3 0 0 0
LO2 5 0 0 0 0 0 0 0 0 0 0 0
LO3 5 0 0 0 0 0 4 0 0 0 0 0
LO4 5 5 0 0 0 0 0 0 0 0 0 0
LO5 5 5 0 0 0 0 0 0 0 0 0 0
LO6 5 5 0 0 0 0 0 0 0 0 0 0
LO7 5 5 0 0 0 0 2 2 0 0 0 0
LO8 5 5 0 0 0 0 0 0 0 0 0 0
LO9 5 5 0 0 0 0 0 0 0 0 0 0
LO10 0 0 0 0 0 0 0 0 0 0 0 0
LO: Learning Objectives PQ: Program Qualifications
Contribution Level: 1 Very Low 2 Low 3 Medium 4 High 5 Very High
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